ReviewAntioxidants (Basel, Switzerland)2018
Monocyte Subsets in Atherosclerosis and Modification with Exercise in Humans.
Review in Antioxidants (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 28 citations in OpenAlex.
- Immune system benefits of pulmonary rehabilitation in chronic obstructive pulmonary disease.Experimental physiology · 2026Review
- Phenotypic Profiling and Activation-Associated Expression of CD99 Ligands on Human Leukocytes.Biology · 2025Article
- Unveiling the role of exercise in modulating plasma heat shock protein 27 levels: insights for exercise immunology and cardiovascular health.Molecular and cellular biochemistry · 2025Review
- Association of monocyte-lymphocyte ratio with peripheral arterial disease in US participants: a retrospective cross-sectional study.Frontiers in cardiovascular medicine · 2025Article
- Acute, but not chronic, aerobic exercise alters the impact of ex vivo LDL and fatty acid stimulation on monocytes and macrophages from healthy, young adults.European journal of applied physiology · 2023Article
- Targeting Immune Senescence in Atherosclerosis.International journal of molecular sciences · 2022Review
- Monocyte Phenotypes and Physical Activity in Patients with Carotid Atherosclerosis.Antioxidants (Basel, Switzerland) · 2022Article
- Recent Progress in Applicability of Exercise Immunology and Inflammation Research to Sports Nutrition.Nutrients · 2021Review
- Article
- Identification of Critical Genes and Signaling Pathways in Human Monocytes Following High-Intensity Exercise.Healthcare (Basel, Switzerland) · 2021Article
- Advances in understanding mechanisms and therapeutic targets to treat comorbid depression and cardiovascular disease.Neuroscience and biobehavioral reviews · 2020Review
- Evaluation of Anti-Inflammatory and Atheroprotective Properties of Wheat Gluten Protein Hydrolysates in Primary Human Monocytes.Foods (Basel, Switzerland) · 2020Article
- Characterization and Modulation of Systemic Inflammatory Response to Exhaustive Exercise in Relation to Oxidative Stress.Antioxidants (Basel, Switzerland) · 2020Review
- microRNA-155 Is Decreased During Atherosclerosis Regression and Is Increased in Urinary Extracellular Vesicles During Atherosclerosis Progression.Frontiers in immunology · 2020Article
- Monocytes and macrophages in atherogenesis.Current opinion in lipidology · 2019Review
- Modulation of Nitric Oxide Synthases by Oxidized LDLs: Role in Vascular Inflammation and Atherosclerosis Development.International journal of molecular sciences · 2019Review
- Chronic Inflammation as an Immunological Abnormality and Effectiveness of Exercise.Biomolecules · 2019Review
- Exercise and Inflammation.Antioxidants (Basel, Switzerland) · 2019Article
Corrections and comments
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Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Atherosclerosis is a progressive pathological remodeling of the arteries and one of its hallmarks is the presence of chronic inflammation. Notably, there is an increased proportion and activation state of specific monocyte subsets in systemic blood circulation. Monocyte subsets have distinct contributions to the formation, progression, and destabilization of the atherosclerotic plaque. Strong clinical and epidemiological studies show that regular aerobic exercise mitigates the progression of cardiovascular disease. In fact, aerobic fitness is a powerful predictor of cardiovascular mortality in adults, independent of traditional risk factors such as hypertension and hyperlipidemia. Acute bouts and chronic exercise training modulate monocyte behavior, ranging from their recruitment from the bone marrow or marginal pool, to tissue margination and functional changes in cytokine and chemokine production. Such modulation could reflect a potential mechanism for the cardio-protective effect of exercise on atherosclerosis. This review summarizes the current knowledge of monocyte subsets and highlights what is known about their responses to exercise.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.