ArticleThe Journal of hospital infection2019
Carbapenem-resistant Enterobacteriaceae dispersal from sinks is linked to drain position and drainage rates in a laboratory model system.
Article in The Journal of hospital infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Sanitation, antibiotics, and the end of the antibiotic era.Public health in practice (Oxford, England) · 2026Article
- Evaluation of BD Phoenix CPO Detect and NG-Test CARBA 5 for the detection and classification of carbapenemase-producingMicrobiology spectrum · 2026Article
- Aerosol-based exposure to opportunistic pathogens originating from hospital sink drains.American journal of infection control · 2026Article
- The hospital sink drain microbiome as a melting pot for AMR transmission to nosocomial pathogens.npj antimicrobials and resistance · 2025Review
- Survey of healthcare-associated sink infrastructure, and sink trap antibiotic residues and biochemistry, in twenty-nine UK hospitals.The Journal of hospital infection · 2025Article
- Nosocomial transmission of NDM-1-containing Klebsiella pneumoniae ST147 in a Dutch pediatric oncology center associated with patients from Ukraine.BMC infectious diseases · 2024Article
- Does Antibiotic Use Contribute to Biofilm Resistance in Sink Drains? A Case Study from Four German Hospital Wards.Antibiotics (Basel, Switzerland) · 2024Article
- Article
- How biofilm changes our understanding of cleaning and disinfection.Antimicrobial resistance and infection control · 2023Review
- The Challenge of Overcoming Antibiotic Resistance in Carbapenem-Resistant Gram-Negative Bacteria: "Attack on Titan".Microorganisms · 2023Review
- Multicentre genetic diversity study of carbapenem-resistant Enterobacterales: predominance of untypeable pUVA-likeJAC-antimicrobial resistance · 2023Article
- Containment of a Verona Integron-Encoded Metallo-Beta-Lactamase-ProducingOpen forum infectious diseases · 2023Article
- Predominance of Multidrug-Resistant Gram-Negative Bacteria on Contaminated Surfaces at a Tertiary Hospital in Tanzania: A Call to Strengthening Environmental Infection Prevention and Control Measures.Current microbiology · 2023Article
- Aspects and problems associated with the water services to be considered in intensive care units.Journal of infection prevention · 2023Article
- Dialysis Water Supply Faucet as Reservoir for Carbapenemase-Producing Pseudomonas aeruginosa.Emerging infectious diseases · 2022Article
- Genomic Investigation and Successful Containment of an Intermittent Common Source Outbreak of OXA-48-Producing Enterobacter cloacae Related to Hospital Shower Drains.Microbiology spectrum · 2021Article
- Migration ofMicroorganisms · 2021Article
- Role of the kitchen environment.Infection prevention in practice · 2021Article
- Long-Term Exposure to Octenidine in a Simulated Sink Trap Environment Results in Selection of Pseudomonas aeruginosa,Applied and environmental microbiology · 2021Article
- Unintended consequences of infection prevention and control measures during COVID-19 pandemic.American journal of infection control · 2021Article
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7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHospital sinks, waste traps and drains can harbour carbapenem-resistant Enterobacteriaceae (CRE).
aimTo investigate the dispersal of CRE from sinks in which water delivered from the tap flows directly into the drain and from clinical handwash basins with the drain at the rear. The effect of fast and slow drainage rates was also assessed.
methodsWaste traps, known to be colonized with CRE, were taken from a hospital and installed within a model laboratory system. New waste traps were also installed and artificially inoculated with CRE. The potential for bacteria to be dispersed from sinks was assessed using cyclone air samplers and/or settle plates.
findingsWhen the waste traps were artificially contaminated and CRE colonization was confined to the waste trap water, significantly fewer bacteria were dispersed from sinks that drained quickly (P = 0.004) and/or from rear-draining sinks (P = 0.002). When the waste traps were naturally contaminated and CRE colonized the trap, pipework and drain, there was significant interaction between sink drainage and position of the drain (P < 0.001). When drainage was slow, dispersal from rear-draining sinks was almost 30-fold less than from sinks with the drain underneath the tap (P < 0.001). When drainage was fast, rear-draining sinks again released comparatively fewer CRE, although, in this case, the difference was not statistically significant (P = 0.7). Contaminated splashes travelled up to 1 m from the sink.
conclusionSlow drainage rates and sink designs with the drain directly underneath the tap increase the risk of CRE present in waste traps and drains contaminating the ward environment.
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