Evidence map›Paper›PMID 30571765›Full record

ArticlePloS one2018

Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a "Grg-mediated repression map" in the mouse telencephalon.

Charalampos Chrysovalantis Chytoudis-Peroudis, Nikistratos Siskos, Konstantinos Kalyviotis, Ioannis Fysekis, Petros Ypsilantis, Constantinos Simopoulos, George Skavdis, Maria E Grigoriou

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Novel Insights into Emx2 and Dmrta2 Cooperation during Cortex Development and Evidence for Dmrta2 Function in the Choroid Plexus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Charalampos Chrysovalantis Chytoudis-PeroudisDepartment of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Nikistratos SiskosDepartment of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.ORCID 0000-0001-9301-314X
Konstantinos KalyviotisDepartment of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Ioannis FysekisDepartment of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Petros YpsilantisSchool of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
Constantinos SimopoulosSchool of Medicine, Democritus University of Thrace, Alexandroupolis, Greece.
George SkavdisDepartment of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.
Maria E GrigoriouDepartment of Molecular Biology & Genetics, Democritus University of Thrace, Alexandroupolis, Greece.ORCID 0000-0001-6336-5523
Democritus University of Thrace · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The full-length members of the Groucho/Transducin-like Enhancer of split gene family, namely Grg1-4, encode nuclear corepressors that act either directly, via interaction with transcription factors, or indirectly by modifying histone acetylation or chromatin structure. In this work we describe a detailed expression analysis of Grg1-4 family members during embryonic neurogenesis in the developing murine telencephalon. Grg1-4 presented a unique, complex yet overlapping expression pattern; Grg1 and Grg3 were mainly detected in the proliferative zones of the telencephalon, Grg2 mainly in the subpallium and finally, Grg4 mainly in the subpallial post mitotic neurons. In addition, comparative analysis of the expression of Grg1-4 revealed that, at these stages, distinct telencephalic progenitor domains or structures are characterized by the presence of different combinations of Grg repressors, thus forming a "Grg-mediated repression map".

Indexed as

Gene Expression Regulation, DevelopmentalAnimalsEmbryo, NonmammalianFemaleMiceMice, Inbred C57BLNeurogenesisProtein Interaction MapsRepressor ProteinsTelencephalonRepressor Proteins

Identifiers

PMID30571765
PMCPMC6301688
OpenAlexW2905993796

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.