Evidence map›Paper›PMID 30571739›Full record

Observational studyPloS one2018

Global and regional degree of obstruction determined by electrical impedance tomography in patients with obstructive ventilatory defect.

Chao Zhang, Meng Dai, Wei Liu, Xiaohui Bai, Jiaming Wu, Canhua Xu, Junying Xia, Feng Fu, Xuetao Shi, Xiuzhen Dong and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Trial
  2. Trial
  3. [Application of electrical impedance tomography in diagnosis and monitoring of pulmonary diseases].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025
    Review
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  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Chao ZhangDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Meng DaiDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Wei LiuDepartment of respiratory medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Xiaohui BaiThe Fifth People's Hospital of Baoji City, Baoji, Shaanxi, China.
Jiaming WuDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Canhua XuDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Junying XiaDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Feng FuDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Xuetao ShiDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Xiuzhen DongDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.
Faguang JinDepartment of respiratory medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Fusheng YouDepartment of Biomedical Engineering, Fourth Military Medical University, Xi'an, Shaanxi, China.ORCID 0000-0002-6963-068X
Air Force Medical University · CNTang Du Hospital · CNBaoji City Central Hospital · CNGeneral Hospital of Shenyang Military Region · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElectrical impedance tomography is a continuous imaging method capable of measuring lung volume changes. The purpose of this study was to examine whether EIT was capable of evaluating the degree of obstructive ventilatory defect (OVD) on the global and regional level.

methods41 healthy subjects with no lung diseases and 67 subjects suffering from obstructive lung diseases were examined using EIT and spirometry during forced vital capacity (FVC) maneuver. The subjects were divided into control group (n = 41), early airway obstruction group (n = 26), mild group (n = 17), moderate group (n = 16) and severe group (n = 8) according to the degree of obstruction. Forced expiratory volume in 1 second (FEV1) and FEV1/FVC were determined by EIT. The mode index (MI) was proposed to evaluate the degree of global and regional obstruction; the effectiveness of MI was validated by evaluating posture related change of lung emptying capacity in sitting and supine postures; the degree of regional obstruction was determined according to the cut-off values of MI obtained from receiver operating characteristic (ROC) analysis; regional obstruction was located in the four-quadrant region of interest (ROI) and the contour-map ROI with contour lines at the cut-off values of MI.

resultsSignificant differences were found between different groups (P<0.05) and the global MI was 0.93±0.03, 0.86±0.05, 0.81±0.09, 0.73±0.09 and 0.60±0.11 (mean ±SD), respectively. The cut-off MI value was 0.90, 0.83, 0.77, and 0.65, respectively.

conclusionThe results indicated the potential of EIT to evaluate the degree of obstruction in patients with obstructive ventilatory defect on the global and regional level.

Indexed as

Electric ImpedanceAdultFeasibility StudiesForced Expiratory VolumeHealthy VolunteersHumansLungLung Diseases, ObstructiveMiddle AgedPilot ProjectsSpirometryTomographyTomography, X-Ray ComputedVital Capacity

Identifiers

PMID30571739
PMCPMC6301672
OpenAlexW2906329291

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.