Evidence map›Paper›PMID 30571523›Full record

ArticleCirculation2018

Inflammation, Inflammasome Activation, and Atrial Fibrillation.

David R Van Wagoner, Mina K Chung

Registry-linked trialAbstract readEditorialComment
In one paragraph

Article in Circulation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04766814 (Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial Fibrillation Patients and Controls), which is not on this map. Cited by 42 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04766814 completednot on this mapstarted 2021, after this paper: background citation

Epigenetic Analysis of Regulation of the Inflammasome-activating NLRP3 Gene in Monocytes From Atrial Fibrillation Patients and Controls

TypeobservationalSponsorTulane UniversityRan2021 to 2024Enrolled29ConditionsAtrial Fibrillation, Arrhythmia
3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. IFNγEuropean heart journal open · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Prevention of New-Onset Heart Failure in Atrial Fibrillation: The Role of Pharmacological Management.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2025
    Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Effect of nutritional status on adverse clinical events in elderly patients with nonvalvular atrial fibrillation: A retrospective cohort study.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2024
    Observational
  17. Article
  18. Article
  19. Article
  20. Rivaroxaban Plasma Concentration and Clinical Outcomes on Older Patients with Non-valvular Atrial Fibrillation and Pulmonary Infection.American journal of cardiovascular drugs : drugs, devices, and other interventions · 2024
    Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

David R Van WagonerDepartments of Molecular Cardiology, Lerner Research Institute (D.R.V.W., M.K.C.), Cleveland Clinic, OH.
Mina K ChungDepartments of Molecular Cardiology, Lerner Research Institute (D.R.V.W., M.K.C.), Cleveland Clinic, OH.

Funding

Functional Genomics of Atrial Fibrillation in Human AtriaR01HL111314 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2012 to 2019
$6.1M
Genetics of Atrial FibrillationR01HL090620 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2008 to 2012
$2.9M
NHLBI NIH HHS R01 HL090620NHLBI NIH HHS R01 HL111314
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Atrial FibrillationInflammasomesHumansInflammationMyocytes, CardiacNLR Family, Pyrin Domain-Containing 3 ProteinInflammasomesNLR Family, Pyrin Domain-Containing 3 ProteinNLRP3 protein, humanatrial fibrillationC-reactive proteinEditorialsinflammasomesinflammationinterleukins

Identifiers

PMID30571523
PMCPMC6334772

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.