Evidence map›Paper›PMID 30571497›Full record

ArticleJournal of the American Heart Association2018

Temperature and Precipitation Associate With Ischemic Stroke Outcomes in the United States.

Stacy Y Chu, Margueritte Cox, Gregg C Fonarow, Eric E Smith, Lee Schwamm, Deepak L Bhatt, Roland A Matsouaka, Ying Xian, Kevin N Sheth

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Wildfire smoke PMScience advances · 2026
    Article
  2. Weathering the storm: Effect of climate change on acute stroke care and stroke rehabilitation.PM & R : the journal of injury, function, and rehabilitation · 2026
    Review
  3. Article
  4. Precipitation, EMS use, and time to presentation of Acute Ischemic stroke in the get with the guidelines-stroke registry.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2025
    Article
  5. Article
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  8. Emerging Stroke Risk Factors: A Focus on Infectious and Environmental Determinants.Journal of cardiovascular development and disease · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Stacy Y Chu1 Department of Neurology Yale School of Medicine New Haven CT.
Margueritte Cox2 Outcomes Research and Assessment Group Duke Clinical Research Institute Durham NC.
Gregg C Fonarow3 Division of Cardiology Department of Medicine UCLA Health Los Angeles CA.
Eric E Smith4 Department of Clinical Neurosciences Hotchkiss Brain Institute University of Calgary Alberta Canada.
Lee Schwamm5 Division of Stroke Department of Neurology Massachusetts General Hospital Boston MA.
Deepak L Bhatt6 Brigham and Women's Hospital Heart & Vascular Center Harvard Medical School Boston MA.
Roland A Matsouaka2 Outcomes Research and Assessment Group Duke Clinical Research Institute Durham NC.
Ying Xian2 Outcomes Research and Assessment Group Duke Clinical Research Institute Durham NC.
Kevin N Sheth8 Division of Neurocritical Care and Emergency Neurology Department of Neurology Yale School of Medicine New Haven CT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background There is disagreement in the literature about the relationship between strokes and seasonal conditions. We sought to (1) describe seasonal patterns of stroke in the United States, and (2) determine the relationship between weather variables and stroke outcomes. Methods and Results We performed a cross-sectional study using Get With The Guidelines-Stroke data from 896 hospitals across the continental United States. We examined effects of season, climate region, and climate variables on stroke outcomes. We identified 457 638 patients admitted from 2011 to 2015 with ischemic stroke. There was a higher frequency of admissions in winter (116 862 in winter versus 113 689 in spring, 113 569 in summer, and 113 518 in fall; P<0.0001). Winter was associated with higher odds of in-hospital mortality (odds ratio [OR] 1.08 relative to spring, confidence interval [ CI ] 1.04-1.13, P=0.0004) and lower odds of discharge home ( OR 0.92, CI 0.91-0.94, P<0.0001) or independent ambulation at discharge ( OR 0.96, CI 0.94-0.98, P=0.0006). These differences were attenuated after adjusting for climate region and case mix and became inconsistent after controlling for weather variables. Temperature and precipitation were independently associated with outcome after multivariable analysis, with increases in temperature and precipitation associated with lower odds of mortality ( OR 0.95, CI 0.93-0.97, P<0.0001 and OR 0.95, CI 0.90-1.00, P=0.035, respectively). Conclusions Admissions for ischemic stroke were more frequent in the winter. Warmer and wetter weather conditions were independently associated with better outcomes. Further studies should aim to identify sensitive populations and inform public health measures aimed at resource allocation, readiness, and adaptive strategies.

Indexed as

Climatic ProcessesAgedCross-Sectional StudiesFemaleHospital MortalityHumansMaleMultivariate AnalysisOdds RatioRainRisk FactorsSeasonsStrokeTemperatureUnited Statescerebrovascular diseaseenvironmentepidemiologyischemic strokeseasonal variation

Identifiers

PMID30571497
PMCPMC6404452

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.