Evidence map›Paper›PMID 30571481›Full record

ArticleJournal of the American Heart Association2018

Temporary Mechanical Circulatory Support for Refractory Cardiogenic Shock Before Left Ventricular Assist Device Surgery.

Saraschandra Vallabhajosyula, Shilpkumar Arora, Sopan Lahewala, Varun Kumar, Ghanshyam P S Shantha, Jacob C Jentzer, John M Stulak, Bernard J Gersh, Rajiv Gulati, Charanjit S Rihal and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed, 3 pooled it
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 3 syntheses or guidelines pooled it, 78 citations in OpenAlex.

  1. Pooled it
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  3. Reporting of sex as a variable in cardiovascular studies using cultured cells: A systematic review.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Pooled it
  4. Article
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  8. Article
  9. Review
  10. Role of acute mechanical circulatory support devices in cardiogenic shock.Indian journal of thoracic and cardiovascular surgery · 2023
    Review
  11. Article
  12. Extracorporeal membrane oxygenation as a bridge to durable left ventricular assist device implantation in INTERMACS-1 patients.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2022
    Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Saraschandra Vallabhajosyula1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Shilpkumar Arora3 Division of Cardiovascular Diseases Robert Packer Hospital/Guthrie Clinic Towanda PA.
Sopan Lahewala4 Division of Cardiovascular Diseases Jersey City Medical Center Jersey City NJ.
Varun Kumar3 Division of Cardiovascular Diseases Robert Packer Hospital/Guthrie Clinic Towanda PA.
Ghanshyam P S Shantha5 Division of Cardiovascular Diseases University of Iowa Carver College of Medicine Iowa City IA.
Jacob C Jentzer1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
John M Stulak6 Department of Cardiovascular Surgery Mayo Clinic Rochester MN.
Bernard J Gersh1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Rajiv Gulati1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Charanjit S Rihal1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Abhiram Prasad1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Abhishek J Deshmukh1 Department of Cardiovascular Medicine Mayo Clinic Rochester MN.
Mayo Clinic · USMayo Clinic in Arizona · USSUNY Upstate Medical University · USWinnMed · USJersey City Medical Center · USUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background There are limited data on the role of temporary mechanical circulatory support ( MCS ) devices for cardiogenic shock before left ventricular assist device ( LVAD ) surgery. This study sought to evaluate the trends of use and outcomes of MCS in cardiogenic shock before LVAD surgery. Methods and Results This was a retrospective cohort study from 2005 to 2014 using the National Inpatient Sample (20% stratified sample of US hospitals). This study identified admissions undergoing LVAD surgery with preoperative cardiogenic shock. Admissions for other cardiac surgery and heart transplant were excluded. Temporary MCS was identified using administrative codes. The primary outcome was hospital mortality and secondary outcomes were hospital costs and lengths of stay in admissions with and without MCS use. In this 10-year period, 9753 admissions were identified with 40.6% requiring pre- LVAD MCS . There was a temporal increase in the frequency of cardiogenic shock associated with an increase in non-intra-aortic balloon pump MCS devices. The cohort receiving MCS had greater in-hospital myocardial infarction, ventricular arrhythmias, and use of coronary angiography. On multivariable analysis, older age, myocardial infarction, and need for MCS devices were independently predictive of higher in-hospital mortality. In 696 propensity-matched pairs, use of MCS was predictive of higher in-hospital mortality (odds ratio 1.4 [95% confidence interval 1.1-1.6]; P=0.02) and higher hospital costs, but similar lengths of stay. Conclusions In patients with cardiogenic shock bridged to LVAD therapy, there was a steady increase in preoperative MCS use. Use of MCS identified patients at higher risk for in-hospital mortality and greater resource utilization.

Indexed as

Extracorporeal CirculationHeart-Assist DevicesFemaleHospital MortalityHumansMaleMiddle AgedProsthesis ImplantationRisk FactorsShock, Cardiogeniccardiogenic shockcritical caredestination therapyleft ventricular assist devicemechanical circulatory support

Identifiers

PMID30571481
PMCPMC6404446
OpenAlexW2905211482

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.