Evidence map›Paper›PMID 30571387›Full record

ArticleJournal of the American Heart Association2018

Adjudicated Heart Failure in HIV-Infected and Uninfected Men and Women.

Matthew J Feinstein, Alexandra B Steverson, Hongyan Ning, Anna E Pawlowski, Daniel Schneider, Faraz S Ahmad, Jes M Sanders, Arjun Sinha, Robin M Nance, Chad J Achenbach and 9 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed, 4 pooled it
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed, 4 syntheses or guidelines pooled it, 90 citations in OpenAlex.

  1. Pooled it
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  7. Observational
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  18. Review
  19. Review
  20. Cardiometabolic health in people with HIV: expert consensus review.The Journal of antimicrobial chemotherapy · 2024
    Review

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 7 institutions in 1 country.

Matthew J Feinstein1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Alexandra B Steverson3 Department of Medicine University of California-San Francisco School of Medicine San Francisco CA.
Hongyan Ning2 Department of Preventive Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Anna E Pawlowski4 Northwestern Medicine Enterprise Data Warehouse Northwestern University Feinberg School of Medicine Chicago IL.
Daniel Schneider4 Northwestern Medicine Enterprise Data Warehouse Northwestern University Feinberg School of Medicine Chicago IL.
Faraz S Ahmad1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Jes M Sanders1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Arjun Sinha1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Robin M Nance5 Department of Medicine University of Washington School of Medicine Seattle WA.
Chad J Achenbach1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
J A Christopher Delaney5 Department of Medicine University of Washington School of Medicine Seattle WA.
Susan R Heckbert6 Department of Epidemiology University of Washington School of Public Health Seattle WA.
Sanjiv J Shah1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
David B Hanna7 Department of Epidemiology and Population Health Albert Einstein College of Medicine Bronx NY.
Priscilla Y Hsue3 Department of Medicine University of California-San Francisco School of Medicine San Francisco CA.
Gerald S Bloomfield8 Duke University School of Medicine Duke Clinical research Institute and Duke Global Health Institute Durham NC.
Chris T Longenecker9 Department of Medicine Case Western Reserve University School of Medicine Cleveland OH.
Heidi M Crane5 Department of Medicine University of Washington School of Medicine Seattle WA.
Donald M Lloyd-Jones1 Department of Medicine Northwestern University Feinberg School of Medicine Chicago IL.
Northwestern University · USUniversity of Washington · USUniversity of California, San Francisco · USAlbert Einstein College of Medicine · USDuke University · USNorthwestern Medicine · USUniversity School · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Virology and Immunology Technology CoreP30AI117943 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael E Newcomb · 2015 to 2026
$38.4M
Prediction of heart failure in HIV-infected individualsK01HL137557 · NHLBI · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI HANNA, DAVID B. · 2017 to 2020
$711k
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS K01 HL137557NIAID NIH HHS P30 AI117943
6 · The paper itself

Abstract

Background HIV is associated with elevated risk of heart failure ( HF ). Despite poor agreement between automated, administrative code-based HF definitions and physician-adjudicated HF , no studies have evaluated incident adjudicated HF for people living with HIV ( PLWH ). Methods and Results We analyzed PLWH and uninfected controls receiving care in an urban medical system from January 1, 2000, to July 12, 2016. Physicians reviewed data from medical records to adjudicate HF diagnoses. We used multivariable-adjusted Cox models to analyze incident HF for PLWH versus controls and HIV -related factors associated with incident HF . We also analyzed the performance of automated versus physician-adjudicated HF definitions. Incident adjudicated HF occurred in 97 of 4640 PLWH (2.1%; mean: 6.8 years to HF ) and 55 of 4250 controls (1.3%; mean: 6.7 years to HF ; multivariable-adjusted hazard ratio: 2.10; 95% confidence interval, 1.38-3.21). Among PLWH , higher HIV viral load ( hazard ratio per log

Indexed as

AdultCohort StudiesFemaleHeart FailureHIV InfectionsHumansIncidenceMaleRisk Assessmentheart failureHIVimmunologyinflammation

Identifiers

PMID30571387
PMCPMC6404176
OpenAlexW2899463601

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.