ArticleHypertension (Dallas, Tex. : 1979)2018
Impact of Preeclampsia on Long-Term Cognitive Function.
Article in Hypertension (Dallas, Tex. : 1979), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
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Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it, 61 citations in OpenAlex.
- The Utility of Maternal Blood S100B in Women with Suspected or Established Preeclampsia-A Systematic Review.Biomolecules · 2025Pooled it
- Temporal patterns of pre- and post-natal target organ damage associated with hypertensive pregnancy: a systematic review.European journal of preventive cardiology · 2024Pooled it
- Hypertensive Disorders of Pregnancy and Incident Dementia.JAMA network open · 2026Article
- Impaired Hearing and Systolic Blood Pressure as Potential Markers of Cerebral Infarction After Eclampsia: A Cross-Sectional Study.BJOG : an international journal of obstetrics and gynaecology · 2026Observational
- Long-term neurological consequences of hypertensive disorders of pregnancy: Implications for postpartum monitoring and intervention.World journal of methodology · 2026Article
- Preeclampsia as a reversible risk factor for Alzheimer's disease: A prospective MRI study on morphological changes of the cerebral cortex and impairment of cognitive functions.The journal of prevention of Alzheimer's disease · 2026Article
- Adverse Pregnancy Outcomes and Cognitive Change in Older Women.Journal of women's health (2002) · 2026Article
- The neuro-immune axis in preeclampsia: from the maternal-fetal interface to systemic dysregulation.Frontiers in immunology · 2026Review
- Article
- Sleep, physical activity, and pregnancy symptoms: Factors associated with cognitive performance in early pregnancy.Midwifery · 2025Article
- Integrated multi-omics analysis reveals immunovascular mechanisms of the placenta-maternal brain axis and lifespan neurobehavior changes in a mouse model of preeclampsia.Neuroscience · 2025Article
- Circ_0008440 Inhibits Proliferation and Promotes Apoptosis of Trophoblast Cells through the miR-194-5p/PFKFB2 Axis.Reproductive sciences (Thousand Oaks, Calif.) · 2025Article
- Hypertensive Disorders of Pregnancy and Brain Health in Midlife: The CARDIA Study.Hypertension (Dallas, Tex. : 1979) · 2025Article
- Preeclampsia and the Long-Term Risk of Developing Neurological Disorders Requiring Hospital Admission.Neuroepidemiology · 2025Article
- Maternal and fetal neurocognitive outcomes in preeclampsia and eclampsia; a narrative review of current evidence.European journal of medical research · 2024Review
- Postpartum and interpregnancy care of women with a history of hypertensive disorders of pregnancy.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Dementia: a looming threat for women with hypertensive disorders of pregnancy?Hypertension research : official journal of the Japanese Society of Hypertension · 2024Article
- Hypertensive disorders of pregnancy and midlife maternal cognition in a prospective cohort study.Journal of clinical hypertension (Greenwich, Conn.) · 2024Article
- Parity and Risk of Dementia in Women: The Atherosclerosis Risk in Communities Study.Journal of women's health (2002) · 2023Article
- Longitudinal cognitive evaluation before and after delivery among people with preeclampsia.American journal of obstetrics & gynecology MFM · 2023Observational
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Preeclampsia increases a woman's risk of stroke and leads to short-term cognitive complaints. Our objective was to assess the impact of preeclampsia on long-term cognitive performance. This is a retrospective cohort study using data from the Coronary Artery Risk Development in Young Adults cohort of healthy individuals (18-30 years) recruited from the general population in 3 cities in the United States, followed for 25 years (1985-2010). Psychomotor speed (Digit Symbol Substitution Test), executive function (Stroop Test), and memory (Rey Auditory Verbal Learning Test) were contrasted between women with and without preeclampsia using multivariate linear regression. We included 568 parous women (193 with preeclampsia and 375 with normotensive pregnancy) without baseline neurological disease or depression matched according to delivery period. Approximately 18 years after delivery, preeclamptic women scored significantly lower on Digit Symbol Substitution Test than women with normotensive pregnancy (73.21±14.79 versus 75.87±15.22; P=0.047) and on the third trial of Stroop Test (correct answers: 38.85±3.62 versus 39.42±1.87; P=0.014; completion time: 44.02±10.48 versus 41.62±10.61 seconds; P=0.01), but there were no differences in Rey Auditory Verbal Learning Test. These differences were attenuated after adjustment for age, body mass index, hypertension, education, and depression. Similar differences in neurocognitive scores were noted between women with other hypertensive disorders of pregnancy and normotensive pregnancy. Hypertension in pregnancy does not seem to be independently associated with neurocognitive impairment later in life.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.