Evidence map›Paper›PMID 30571194›Full record

ArticleCirculation. Heart failure2018

Society of Thoracic Surgeons Risk Score and EuroSCORE-2 Appropriately Assess 30-Day Postoperative Mortality in the STICH Trial and a Contemporary Cohort of Patients With Left Ventricular Dysfunction Undergoing Surgical Revascularization.

Nadia Bouabdallaoui, Susanna R Stevens, Torsten Doenst, Mark C Petrie, Nawwar Al-Attar, Imtiaz S Ali, Andrew P Ambrosy, Anna K Barton, Raymond Cartier, Alexander Cherniavsky and 18 more

2 registry-linked trialsOpen access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Circulation. Heart failure, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00023595 phase3completednot on this map

Surgical Treatment for Ischemic Heart Failure (STICH)

TypeinterventionalSponsorDuke UniversityRan2002 to 2015Enrolled2,136ConditionsCardiovascular Diseases, Coronary Disease, Heart Failure, Congestive, Heart DiseasesArmsCABG surgery plus MED, Active Medication Alone, CABG plus MED and SVR
NCT04499027 completednot on this mapstarted 2020, after this paper: background citation

Prognostic Value of Lung Ultrasound in Predicting Intensive Care Unit Length of Stay in Adult Cardiac Surgery: A Prospective Observational Study

TypeobservationalSponsorFayoum University HospitalRan2020 to 2022Enrolled191ConditionsCoronary Artery Disease, Valvular Heart DiseaseArmsLung ultrasound scan
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Surgical Risk and Revascularization-An Update.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
  4. Intravascular lithotripsy enables safe and effective transfemoral aortic valve replacement.Clinical research in cardiology : official journal of the German Cardiac Society · 2025
    Article
  5. Surgical Risk and Long-Term Mortality With PCI and CABG in Ischemic Left Ventricular Systolic Dysfunction.Journal of the Society for Cardiovascular Angiography & Interventions · 2025
    Article
  6. Review
  7. Early Mortality in Cardiac Surgery - Is Lactate Significant?Brazilian journal of cardiovascular surgery · 2024
    Article
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Building and Optimizing the Interdisciplinary Heart Team.Journal of the Society for Cardiovascular Angiography & Interventions
    Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 3 institutions in 2 countries.

Nadia BouabdallaouiDepartments of Medicine, ontreal Heart Institute, University of Montreal, Canada (N.B., J.L.R.).
Susanna R StevensM. Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC. (S.R.S.).
Torsten DoenstDepartment of Cardiothoracic Surgery, Jena University Hospital, Friedrich-Schiller-University Jena, Germany (T.D., P.H.).
Mark C PetrieDepartment of Cardiology, Institute of Cardiovascular and Medical Sciences, University of Glasgow, United Kingdom (M.C.P.).
Nawwar Al-AttarDepartment of Cardiology, Golden Jubilee National Hospital, Glasgow, United Kingdom (M.C.P., N.A.-A, A.K.B.).
Imtiaz S AliSection of Cardiac Surgery, Department of Cardiac Sciences, Libin CV Institute, University of Calgary, Canada (I.S.A.).
Andrew P AmbrosyDepartment of Medicine, Duke University School of Medicine, Durham, NC. (A.P.A., E.J.V.).
Anna K BartonDepartment of Cardiology, Golden Jubilee National Hospital, Glasgow, United Kingdom (M.C.P., N.A.-A, A.K.B.).
Raymond CartierCardiac Surgery, ontreal Heart Institute, University of Montreal, Canada (R.C.).
Alexander CherniavskyResearch Institute of Circulation Pathology, Novosibirsk, Russia (A.C.).
Pierre DemondionDepartment of Cardiac Surgery, La Pitié Salpêtrière, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie-Paris 6, France (P.D.).
Patrice Desvigne-NickensNational Heart, Lung, and Blood Institute, Bethesda, MD (P.D.-N.).
Robert R FavaloroDepartment of Cardiac Surgery, University Hospital Favaloro Foundation, Buenos Aires, Argentina (R.R.F.).
Sinisa GradinacDedinje Cardiovascular Institute, University of Belgrade School of Medicine, Serbia (S.G.).
Petra HeinischDepartment of Cardiothoracic Surgery, Jena University Hospital, Friedrich-Schiller-University Jena, Germany (T.D., P.H.).
Anil JainDepartment of Cardiac Surgery, SAL Hospital and Medical Institute, Ahmedabad, India (A.J.).
Marek JasinskiDepartment of Cardiac Surgery, Wroclaw Medical University, Poland (M.J.).
Jerome JouanDepartment of Cardiovascular Surgery, Georges Pompidou European Hospital and University Paris-Descartes, Sorbonne Paris-Cité, France (J.J.).
Renato A K KalilPostgraduate Program, Instituto de Cardiologia/FUC and UFCSPA, Porto Alegre, Brazil (R.A.K.K.).
Lorenzo MenicantiDepartment of Cardiac Surgery, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy (L.M.).
Robert E MichlerDepartment of Cardiothoracic and Vascular Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, New York City, NY (R.E.M.).
Vivek RaoDivision of Cardiovascular Surgery, Peter Munk Cardiac Centre, Toronto General Institute, University Health Network, University of Toronto, Canada (V.R.).
Peter K SmithDepartment of Surgery, Duke University School of Medicine, Durham, NC. (P.K.S.).
Marian ZembalaDepartment of Cardiac, Vascular and Endovascular Surgery and Transplantology, Silesian Center for Heart Diseases in Zabrze, Poland Medical University of Silesia in Katowice, Poland (M.Z.).
Eric J VelazquezDepartment of Medicine, Duke University School of Medicine, Durham, NC. (A.P.A., E.J.V.).
Hussein R Al-KhalidiDepartments of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC. (H.R.A.-K.).
Jean L RouleauDepartments of Medicine, ontreal Heart Institute, University of Montreal, Canada (N.B., J.L.R.).
STICH Trial Investigators
Duke University · USUniversité de Montréal · CAClinical Research Institute · US

Funding

STICH Trial-Coordinating CenterU01HL069015 · NHLBI · DUKE UNIVERSITY · PI JONES, ROBERT H · 2002 to 2011
$27.3M
STICHESR01HL105853 · NHLBI · DUKE UNIVERSITY · PI AL-KHALIDI, HUSSEIN · 2011 to 2015
$10.2M
STICH Trial-Statistical and Data Coordinatiing CenterU01HL069013 · NHLBI · DUKE UNIVERSITY · PI LEE, KERRY L · 2002 to 2010
$5.0M
NHLBI NIH HHS R01 HL105853NHLBI NIH HHS U01 HL069013NHLBI NIH HHS U01 HL069015
6 · The paper itself

Abstract

backgroundThe STICH trial (Surgical Treatment for Ischemic Heart Failure) demonstrated a survival benefit of coronary artery bypass grafting in patients with ischemic cardiomyopathy and left ventricular dysfunction. The Society of Thoracic Surgeons (STS) risk score and the EuroSCORE-2 (ES2) are used for risk assessment in cardiac surgery, with little information available about their accuracy in patients with left ventricular dysfunction. We assessed the ability of the STS score and ES2 to evaluate 30-day postoperative mortality risk in STICH and a contemporary cohort (CC) of patients with a left ventricle ejection fraction ≤35% undergoing coronary artery bypass grafting outside of a trial setting. METHODS AND

resultsThe STS and ES2 scores were calculated for 814 STICH patients and 1246 consecutive patients in a CC. There were marked variations in 30-day postoperative mortality risk from 1 patient to another. The STS scores consistently calculated lower risk scores than ES2 (1.5 versus 2.9 for the CC and 0.9 versus 2.4 for the STICH cohort), and underestimated postoperative mortality risk. The STS and ES2 scores had moderately good C statistics: CC (0.727, 95% CI: 0.650-0.803 for STS, and 0.707, 95% CI: 0.620-0.795 for ES2); STICH (0.744, 95% CI: 0.677-0.812, for STS and 0.736, 95% CI: 0.665-0.808 for ES2). Despite the CC patients having higher STS and ES2 scores than STICH patients, mortality (3.5%) was lower than that of STICH (4.8%), suggesting a possible decrease in postoperative mortality over the past decade.

conclusionsThe 30-day postoperative mortality risk of coronary artery bypass grafting in patients with left ventricular dysfunction varies markedly. Both the STS and ES2 score are effective in evaluating risk, although the STS score tend to underestimate risk. CLINICAL

trial registrationURL: https://www.clinicaltrials.gov. Unique identifier: NCT00023595.

Indexed as

Postoperative PeriodAgedCardiac Surgical ProceduresCoronary Artery BypassFemaleHeart FailureHumansMaleMiddle AgedMyocardial IschemiaRisk AssessmentRisk FactorsSurgeonsVentricular Dysfunction, LeftVentricular Function, Leftcoronary artery bypasscoronary artery diseaseheart failurerisk stratification

Identifiers

PMID30571194
PMCPMC6309904
OpenAlexW2901801132

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.