Evidence map›Paper›PMID 30570274›Full record

ArticleExperimental and clinical psychopharmacology2019

Evaluation of mifepristone effects on alcohol-seeking and self-administration in baboons.

August F Holtyn, Elise M Weerts

Open access · hybridAbstract read
In one paragraph

Article in Experimental and clinical psychopharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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  13. Mifepristone Decreases Chronic Voluntary Ethanol Consumption in Rhesus Macaques.The Journal of pharmacology and experimental therapeutics · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

August F HoltynDepartment of Psychiatry and Behavioral Sciences.
Elise M WeertsDepartment of Psychiatry and Behavioral Sciences.ORCID 0000-0002-8234-0919

Funding

Preclinical Assessment of Medications for Alcohol AbuseR01AA015971 · NIAAA · JOHNS HOPKINS UNIVERSITY · PI WEERTS, ELISE M · 2007 to 2023
$7.7M
National Institutes of Health; National Institute on Alcohol Abuse and AlcoholismNIAAA NIH HHS R01 AA015971
6 · The paper itself

Abstract

Mifepristone, a type II glucocorticoid receptor antagonist, is under investigation as a potential pharmacotherapy for alcohol use disorder. This study examined effects of chronic administration of mifepristone on alcohol-seeking and self-administration in large nonhuman primates. Adult baboons (

Indexed as

Self AdministrationAlcohol DrinkingAlcoholismAnimalsCuesEthanolMaleMifepristonePapioReinforcement ScheduleEthanolMifepristone

Identifiers

PMID30570274
PMCPMC6727199
OpenAlexW2906604245

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.