Evidence map›Paper›PMID 30570200›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2019

Cost-effectiveness of home blood pressure telemonitoring and case management in the secondary prevention of cerebrovascular disease in Canada.

Raj S Padwal, Helen So, Peter W Wood, Finlay A Mcalister, Muzaffar Siddiqui, Colleen M Norris, Tom Jeerakathil, James Stone, Shelley Valaire, Balraj Mann and 2 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05034354 (Development and Feasibility of a Virtual Remote Physiological Monitoring Program of Children With Heart Disease), which is not on this map. Cited by 20 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 3 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05034354 nacompletednot on this mapstarted 2022, after this paper: background citation

Development and Feasibility of a Virtual Remote Physiological Monitoring Program of Children With Heart Disease

TypeinterventionalSponsorUniversity of AlbertaRan2022 to 2025Enrolled23ConditionsPediatric ALL, Congenital Heart Disease, Single-ventricle, Biventricular Congestive Heart FailureArmsRemote physiological monitoring
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 3 syntheses or guidelines pooled it, 35 citations in OpenAlex.

  1. Pooled it
  2. Economic Evaluation of Pharmacist-Led Digital Health Interventions: A Systematic Review.International journal of environmental research and public health · 2022
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  5. Pharmacist-Directed Self-Management of Blood Pressure Versus Conventional Management in Patients with Hypertension: A Randomized Control Trial.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Raj S PadwalDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.ORCID 0000-0003-3541-2817
Helen SoDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Peter W WoodDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Finlay A McalisterDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Muzaffar SiddiquiDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Colleen M NorrisMazankowski Heart Institute, Edmonton, Alberta, Canada.
Tom JeerakathilAlberta Health Services Cardiovascular Health and Stroke Strategic Clinical Network, Edmonton, Alberta, Canada.
James StoneAlberta Health Services Cardiovascular Health and Stroke Strategic Clinical Network, Edmonton, Alberta, Canada.
Shelley ValaireAlberta Health Services Cardiovascular Health and Stroke Strategic Clinical Network, Edmonton, Alberta, Canada.
Balraj MannAlberta Health Services Cardiovascular Health and Stroke Strategic Clinical Network, Edmonton, Alberta, Canada.
Pierre BoulangerDepartment of Computing Science, University of Alberta, Edmonton, Alberta, Canada.
Scott W KlarenbachDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
University of Alberta · CAAlberta Health Services · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Home blood pressure (BP) telemonitoring and pharmacist case management reduce BP, but cost-effectiveness assessments are mixed. We examined the incremental cost-effectiveness of this intervention vs usual care in Canadians with cerebrovascular disease. A Markov decision model cost-utility analysis examining community-residing, high-risk patients with a recent nondisabling cerebrovascular event was created. A lifetime time horizon and health care payer perspective were used. Achieved BP, future cardiovascular risks, and attendant consequences on quality-adjusted life years and Canadian dollar costs were modeled. BP telemonitoring was assumed to occur for 3 months, then quarterly. Life tables were used to determine overall mortality, adjusted by cardiovascular disease mortality. Relative efficacies of intervention-associated BP lowering, resource use, and costs were obtained from Canadian published literature. Reduction in systolic BP of 9.7 mmHg was used in the base case; subsequently, robust sensitivity analyses were conducted. The results showed that, over the lifetime horizon, telemonitoring with case management led to net health care savings of $1929 Canadian and increased per-patient QALYs by 0.83. These findings were robust to sensitivity analysis, with the intervention remaining dominant or highly cost-effective. Increasing telemonitoring costs by 50% still resulted in the intervention being dominant; if the costs of telemonitoring plus case management were 2-3 times base case cost, incremental cost-effectiveness was $1200-$4700 per quality-adjusted life year gained. In conclusion, home BP telemonitoring and pharmacist case management poststroke lowered costs and improved QALYs. Strategies and funding for broad implementation of this dominant strategy should be implemented.

Indexed as

AgedAged, 80 and overBlood Pressure DeterminationCanadaCase ManagementCerebrovascular DisordersCost-Benefit AnalysisFemaleHumansHypertensionMaleMarkov ChainsMiddle AgedMortalityPharmacistsQuality-Adjusted Life Yearsblood pressure telemonitoringcase managementhypertensionpharmacistsecondary preventionstroke

Identifiers

PMID30570200
PMCPMC8030339
OpenAlexW2906298957

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.