ArticleArquivos brasileiros de cardiologia2019
Association Between Non-Dipping and Fragmented QRS Complexes in Prehypertensive Patients.
Article in Arquivos brasileiros de cardiologia, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Fragmented QRS as a Marker of Myocardial Fibrosis in Hypertension: a Systematic Review.Current hypertension reports · 2019Pooled it
- Highlights in the association of fragmented QRS with myocardial fibrosis.Turkish journal of medical sciences · 2022Article
- Electrocardiographic alterations in patients with chronic obstructive pulmonary disease.World journal of cardiology · 2022Article
- Electrocardiographic Localization of Fragmented QRS and the Extent and Severity of Myocardial Damage.Pediatric cardiology · 2021Article
- Characteristics of Circadian Blood Pressure Pattern of Hypertensive Patients According to Localization of Fragmented QRS on Electrocardiography.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2021Article
- Subclinical cardiac structural and electrical abnormalities in fibromyalgia syndromeTurkish journal of medical sciences · 2020Article
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2 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundFragmented QRS (fQRS) is a sign of adverse cardiovascular events in various cardiovascular diseases. It is also associated with increased blood pressure and non-dipping in hypertensive patients. However, no study has investigated the importance of fQRS in prehypertensive patients.
objectivesThe aim of our study is to investigate the relationship between fQRS and non-dipper status in prehypertensive patients.
methodsTwo hundred and sixteen eligible, newly diagnosed prehypertensive patients who underwent 24-hour ambulatory blood pressure monitoring (ABPM) for further evaluation of blood pressure between June 2015 and July 2016 were included into the study. Patients were divided into three groups according to ABPM results: normotensives, dipper prehypertensives, and non-dipper prehypertensives. Groups were compared regarding presence of fQRS on electrocardiography. Additionally, multinomial logistic regression analysis was used to determine the relationship between fQRS and blood pressure pattern in prehypertensive patients.
resultsAccording to ABPM recordings, 61 patients had normotensive blood pressure pattern (systolic blood pressure < 120 mmHg and diastolic blood pressure < 80 mmHg). Of the remaining 155 prehypertensive patients, 83 were dippers and 72 were non-dippers. Non-dipper prehypertensives had a significantly higher frequency of fQRS compared to normotensives (p = 0.048). Furthermore, multinomial logistic regression analysis revealed that fQRS is an independent predictor of non-dipping blood pressure pattern in prehypertensive patients (p = 0.017, OR: 4.071, 95% CI: 1.281-12.936).
conclusionsWe found that fQRS is a predictor of non-dipping in prehypertensives. As a marker of fibrosis and higher fibrotic burden within myocardium, fQRS may be useful in identifying high-risk prehypertensive patients before the development of hypertension.
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