ArticleJournal of medical primatology2019
Effect of maternal obesity on fetal and postnatal baboon (Papio species) early life phenotype.
Article in Journal of medical primatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed.
- The Baboon as a Model to Study Human Health and Complex Disease.American journal of primatology · 2026Review
- Maternal high-fat high-energy diet impairs surfactant maturation in the non-human primate fetal lung.International journal of obesity (2005) · 2026Article
- Maternal Nutrient Excess Induces Stress Signaling and Decreases Mitochondrial Number in Term Fetal Baboon Skeletal Muscle.Biology · 2025Article
- Article
- Neuroactive steroids in the programming of neurodevelopment: implications of maternal obesity.Frontiers in endocrinology · 2025Review
- Maternal obesogenic diet during pregnancy and its impact on fetal hepatic function in baboons.Obesity (Silver Spring, Md.) · 2024Article
- Maternal high fat-high energy diet alters metabolic factors in the non-human primate fetal heart.The Journal of physiology · 2024Article
- Article
- Maternal obesity alters offspring liver and skeletal muscle metabolism in early post-puberty despite maintaining a normal post-weaning dietary lifestyle.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2022Article
- Western diet-induced shifts in the maternal microbiome are associated with altered microRNA expression in baboon placenta and fetal liver.Frontiers in clinical diabetes and healthcare · 2022Article
- Molecular Approaches for the Validation of the Baboon as a Nonhuman Primate Model for the Study of Zika Virus Infection.Frontiers in cellular and infection microbiology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundNon-human primate models of developmental programming by maternal obesity (MO) are needed for translation to human programming outcomes. We present baboon offspring (F1) morphometry, blood cortisol, and adrenocorticotropic hormone (ACTH) from 0.9 gestation to 0-2 years.
methodsControl mothers ate chow; MO mothers ate high-fat high-energy diet pre-pregnancy through lactation.
resultsMaternal obesity mothers weighed more than controls pre-pregnancy. Maternal obesity gestational weight gain was lower with no correlation with fetal or placenta weights. At 0.9 gestation, MO and control F1 morphometry and ACTH were similar. MO-F1 0.9 gestation male cortisol was lower, rising slower from 0-2 years vs control-F1. At birth, male MO-F1 and control-F1 weights were similar, but growth from 0-2 years was steeper in MO-F1; newborn female MO-F1 weighed more than control-F1 but growth from 0-2 years was similar. ACTH did not change in either sex.
conclusionsMaternal obesity produced sexually dimorphic fetal and postnatal growth and hormonal phenotypes.
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