Evidence map›Paper›PMID 30569440›Full record

ArticleClinical rheumatology2019

Symptomatic psoriatic dactylitis is associated with ultrasound determined extra-synovial inflammatory features and shorter disease duration.

Nicolò Girolimetto, Luisa Costa, Luana Mancarella, Olga Addimanda, Paolo Bottiglieri, Francesco Santelli, Riccardo Meliconi, Rosario Peluso, Antonio Del Puente, Pierluigi Macchioni and 4 more

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Article in Clinical rheumatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. New Perspectives on Diagnosing Psoriatic Arthritis by Imaging Techniques.Open access rheumatology : research and reviews · 2021
    Review
  9. Observational
  10. Article
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 5 institutions in 2 countries.

Nicolò GirolimettoDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Luisa CostaDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Luana MancarellaMedicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, Bologna, Italy.
Olga AddimandaMedicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, Bologna, Italy.
Paolo BottiglieriDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Francesco SantelliDepartment of Social Sciences, University Federico II, Naples, Italy.
Riccardo MeliconiMedicine & Rheumatology Unit, Rizzoli Orthopaedic Institute, Bologna, Italy.
Rosario PelusoDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Antonio Del PuenteDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Pierluigi MacchioniDepartment of Rheumatology, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Carlo SalvaraniDepartment of Rheumatology, Azienda USL-IRCCS di Reggio Emilia, Reggio Emilia, Italy.
Dennis McGonagleNIHR Leeds Musculoskeletal Biomedical Research Centre, Leeds Teaching Hospitals Trust and the University of Leeds, Leeds, UK.
Raffaele ScarpaDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy. rscarpa@unina.it.ORCID http://orcid.org/0000-0002-5808-6607
Francesco CasoDepartment of Clinical and Experimental Medicine, Rheumatology Research Unit, University Federico II, Via S. Pansini 5, 80131, Naples, Italy.
Federico II University Hospital · ITIstituto Ortopedico Rizzoli · ITAzienda Sanitaria Unità Locale di Reggio Emilia · ITUniversity of Leeds · GBUniversity of Modena and Reggio Emilia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo explore the link between ultrasonographic features of dactylitis in psoriatic arthritis (PsA) and symptoms, digital tenderness and duration of dactylitis.

methodsForty-eight cases of PsA dactylitis were investigated using high frequency ultrasound (US) both in grey scale (GS) and Power Doppler (PD), evaluating the presence and the degree of flexor tenosynovitis, peri-tendinous oedema, subcutaneous PD, extensor tendon involvement, GS synovitis and intra-articular PD signal (PDS) of the involved digits. Patients were compared according to the presence of local pain and digital tenderness, the duration of dactylitis and the concomitant treatment.

resultsThe presence of pain/tenderness was positively associated with US GS flexor tenosynovitis of grade > 2 (p < 0.001), PD-flexor tenosynovitis (p < 0.001), peri-tendinous oedema (p < 0.001) and subcutaneous PDS (p < 0.001); moreover, it was negatively associated with GS synovitis (p < 0.001) and intra-articular PD (p < 0.001). The same positive and negative association with US findings were found comparing patients with duration of dactylitis shorter or longer than the median (24 weeks) (p < 0.001 for all comparisons).

conclusionsPain and digital tenderness are linked to dactylitis duration and earlier lesions are associated with extra synovial inflammatory changes. These findings suggest a hitherto unappreciated extra synovial basis for symptoms in PsA dactylitis.

Indexed as

AdultAgedArthritis, PsoriaticEdemaFemaleFinger JointHumansMaleMiddle AgedSynovial MembraneSynovitisTendonsTenosynovitisTime FactorsUltrasonographyUltrasonography, DopplerDactylitisDigital tendernessFlexorOedemaPsoriatic arthritisTenosynovitisUltrasound

Identifiers

PMID30569440
OpenAlexW2904311917

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.