ArticleJournal of clinical monitoring and computing2019
Anesthesia depth monitoring using alternative placement of entropy sensors: a prospective study.
Article in Journal of clinical monitoring and computing, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Alternative sensor montage for Index based EEG monitoring. A systematic review.Journal of clinical monitoring and computing · 2024Pooled it
- Indian expert consensus on intra-operative consciousness monitoring using processed electroencephalogram-based indices: A Delphi-based approach.Indian journal of anaesthesia · 2026Article
- End of year summary 2019: anaesthesia and airway management.Journal of clinical monitoring and computing · 2020Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spectral entropy is based on analysis of variations in electroencephalography and frontal electromyography, and is a safe and reliable method for anesthesia depth monitoring. However, standard frontal positioning of entropy electrodes in patients undergoing cardiac surgery is sometimes challenging. The present study aimed to compare standard entropy sensor placement with an alternative (infraorbital) site. This prospective study included 20 patients who underwent cardiovascular surgery at the authors' center. Monitoring was performed with standard and alternative entropy electrode positions from patient admission to surgery to transfer to the intensive care unit. Data were recorded every 15 s; all data were analyzed and compared using Bland-Altman, scatter plot with Pearson correlation coefficient, and sensitivity/specificity analyses. Overall, 20,784 pairs of response entropy (RE) and state entropy (SE) indexes were collected. Bland-Altman analysis revealed a mean difference in RE of 0.37 (95% LOA - 7.09, 7.88) and SE 0.69 (95% LOA - 5.95, 7.31); with 3.46% (720/20,784) RE and 3.40% (706/10,790) SE values lying outside of the limits of agreement. Correlation analysis revealed strong positive correlation in both cases: RE, r = 0.983, p < 0.05; SE, r = 0.984; p < 0.05. Sensitivity/specificity analysis revealed 98.1% sensitivity, 93.3% specificity and 97.1% test efficiency for RE, and 99.2%, 95.1% and 98.5% for SE, respectively. Infraorbital entropy sensor placement in patients undergoing cardiovascular surgery is reliable and effective. The strong positive correlation between the two methods of registration enables alternative entropy measurement when frontal placement is not possible.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.