Evidence map›Paper›PMID 30569412›Full record

ReviewJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2019

State-of-the-art radionuclide imaging in cardiac transthyretin amyloidosis.

Vasvi Singh, Rodney Falk, Marcelo F Di Carli, Marie Kijewski, Claudio Rapezzi, Sharmila Dorbala

Open access · greenAbstract readReview
In one paragraph

Review in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 3 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 3 syntheses or guidelines pooled it, 130 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Preclinical and preliminary clinical evaluation of [European journal of nuclear medicine and molecular imaging · 2026
    Trial
  5. Review
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  9. Prognostic value ofJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2025
    Article
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  11. Effects of tafamidis on serial [European journal of nuclear medicine and molecular imaging · 2025
    Article
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  14. 2025 Update Consensus ofActa Cardiologica Sinica · 2025
    Article
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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Vasvi SinghDivision of Nuclear Medicine and Department of Radiology, Brigham and Women's Hospital, Boston, MA, 2115, USA.
Rodney FalkCardiac Amyloidosis Program, Brigham and Women's Hospital, Boston, MA, 2115, USA.
Marcelo F Di CarliDivision of Nuclear Medicine and Department of Radiology, Brigham and Women's Hospital, Boston, MA, 2115, USA.
Marie KijewskiDivision of Nuclear Medicine and Department of Radiology, Brigham and Women's Hospital, Boston, MA, 2115, USA.
Claudio RapezziCardiology, Department of Experimental, Diagnostic and Specialty Medicine, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
Sharmila DorbalaDivision of Nuclear Medicine and Department of Radiology, Brigham and Women's Hospital, Boston, MA, 2115, USA. sdorbala@bwh.harvard.edu.
Brigham and Women's Hospital · USUniversity of Bologna · IT

Funding

Molecular Imaging of Primary Amyloid CardiomyopathyR01HL130563 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI DORBALA, SHARMILA, FALK, RODNEY H · 2016 to 2019
$3.3M
NHLBI NIH HHS R01 HL130563
6 · The paper itself

Abstract

Cardiac amyloidosis, once considered untreatable, is now gaining well-deserved attention due to advances in imaging and the recent approval of targeted breakthrough therapies. In this paper, we discuss the role of radionuclide imaging in the evaluation and management of patients with the most common form of amyloidosis-cardiac transthyretin amyloidosis (ATTR). We provide a comprehensive summary of the literature interspersed with our institutional experience as appropriate, to deliver our perspective.

Indexed as

Amyloid Neuropathies, FamilialAmyloidosisBone and BonesCardiomyopathiesHeartHumansPrealbuminRadionuclide ImagingTechnetium Tc 99m MedronateTechnetium Tc 99m PyrophosphateTomography, Emission-Computed, Single-PhotonPrealbuminTechnetium Tc 99m MedronateTechnetium Tc 99m PyrophosphateAmyloid heart diseasemodalitiesmolecular imagingPETSPECT

Identifiers

PMID30569412
PMCPMC6541031
OpenAlexW2903969599

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.