Evidence map›Paper›PMID 30569354›Full record

ArticleEnvironmental science and pollution research international2019

Developmental toxicity of the triazole fungicide cyproconazole in embryo-larval stages of zebrafish (Danio rerio).

Fangjie Cao, Christopher L Souders, Pengfei Li, Sen Pang, Lihong Qiu, Christopher J Martyniuk

Abstract read
PubMed Publisher
In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 84 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. RosetteArraybioRxiv : the preprint server for biology · 2024
    Article
  5. Article
  6. Triazole fungicides induce adipogenesis and repress osteoblastogenesis in zebrafish.Toxicological sciences : an official journal of the Society of Toxicology · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Cardiotoxicity of some pesticides and their amelioration.Environmental science and pollution research international · 2021
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Fangjie CaoDepartment of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China.
Christopher L SoudersDepartment of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida Genetics Institute, Interdisciplinary Program in Biomedical Sciences Neuroscience, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32611, USA.
Pengfei LiState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Sen PangDepartment of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China.
Lihong QiuDepartment of Applied Chemistry, College of Science, China Agricultural University, Beijing, 100193, China.
Christopher J MartyniukDepartment of Physiological Sciences and Center for Environmental and Human Toxicology, University of Florida Genetics Institute, Interdisciplinary Program in Biomedical Sciences Neuroscience, College of Veterinary Medicine, University of Florida, Gainesville, FL, 32611, USA. cmartyn@ufl.edu.
University of Florida · USChina Agricultural University · CNChinese Academy of Agricultural Sciences · CN

Funding

China Scholarship Council 201706350062College of Veterinary Medicine, University of Florida CJM
6 · The paper itself

Abstract

Cyproconazole is a triazole fungicide used to protect a diverse range of fruits, vegetables, and grain crops. As such, it has the potential to enter aquatic environments and affect non-target organisms. The objective of this study was to assess the acute toxicity of the triazole fungicide cyproconazole to zebrafish embryos by assessing mortality, developmental defects, morphological abnormality, oxidative respiration, and locomotor activity following a 96-h exposure. Zebrafish embryos at 6-h post-fertilization (hpf) were exposed to either a solvent control (0.1% DMSO, v/v), or one dose of 10, 25, 50, 100, 250, and 500 μM cyproconazole for 96 h. Data indicated that cyproconazole exhibited low toxicity to zebrafish embryos, with a 96-h LC

Indexed as

ZebrafishAnimalsDose-Response Relationship, DrugEmbryonic DevelopmentEmbryo, NonmammalianFungicides, IndustrialLarvaMotor ActivityTriazolesWater Pollutants, ChemicalcyproconazoleFungicides, IndustrialTriazolesWater Pollutants, ChemicalCyproconazoleDevelopmental defectsLocomotor activityMalformationsOxidative respirationZebrafish embryos

Identifiers

PMID30569354
OpenAlexW2903801406

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.