Evidence map›Paper›PMID 30569338›Full record

ArticleClinical oral investigations2019

Association of somatosensory dysfunction with symptom duration in burning mouth syndrome.

Kosuke Watanabe, Noboru Noma, Naohiko Sekine, Daiki Takanezawa, Chisa Hirota, Eli Eliav, Yoshiki Imamura

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Article in Clinical oral investigations, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Kosuke WatanabeDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo, Japan.
Noboru NomaDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo, Japan. noma.noboru@nihon-u.ac.jp.
Naohiko SekineDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo, Japan.
Daiki TakanezawaDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo, Japan.
Chisa HirotaDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo, Japan.
Eli EliavEastman Institute for Oral Health, University of Rochester Medical Center, Rochester, NY, USA.
Yoshiki ImamuraDepartment of Oral Diagnostic Sciences, Nihon University School of Dentistry, Tokyo, Japan.
Nihon University · JPEastman Chemical Company (United States) · US

Funding

Nihon University Multidisciplinary Research Grant 18-014
6 · The paper itself

Abstract

objectivesA standardized battery of quantitative sensory tests developed by the German Research Network on Neuropathic Pain (DFNS) was used to assess the association between somatosensory dysfunction and disease duration in patients with burning mouth syndrome (BMS). MATERIALS AND

methodsThe 28 female participants with BMS were classified according to disease duration: ≤ 6 months (subchronic BMS, n = 15) and > 6 months (chronic BMS, n = 13); 29 age- and sex-matched healthy volunteers (control group) were recruited from staff of a dental hospital. The DFNS quantitative sensory testing protocol was applied at the ulnar surface of the right forearm and the tip of the tongue. Values for BMS patients and controls were compared and analyzed.

resultsThe mechanical detection threshold (MDT) was significantly higher (i.e., loss of sensation) at the tongue tip in the chronic BMS group than in the control group (p = 0.011), whereas mechanical pain sensitivity (MPS) at the forearm was significantly higher (i.e., gain of sensation) in the chronic BMS group than in the control group (Z score = - 2.13 and 1.99, respectively). Multivariate analyses revealed that BMS patients could be discriminated from controls by using pressure pain threshold at the tongue (79.3%) (in the subchronic BMS group) and by MDT and MPS at the tongue tip and MPS at the forearm (96.6 and 89.7%, respectively) (in the chronic BMS group).

conclusionsIn BMS patients with long disease duration, MDT showed loss of sensation. CLINICAL RELEVANCE: Increased MPS suggests that a neuropathic mechanism in the peripheral and central nervous systems is involved in BMS development.

Indexed as

Burning Mouth SyndromePain ThresholdFemaleHumansPainPain MeasurementTongueBurning mouth syndromeGerman Research Network on Neuropathic PainQuantitative sensory testing

Identifiers

PMID30569338
OpenAlexW2905152831

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.