Evidence map›Paper›PMID 30569333›Full record

ReviewDigestive diseases and sciences2019

Duodenoscope-Associated Infections: Update on an Emerging Problem.

M Rubayat Rahman, Abhilash Perisetti, Roxana Coman, Pardeep Bansal, Rajiv Chhabra, Hemant Goyal

Abstract readReview
PubMed Publisher
In one paragraph

Review in Digestive diseases and sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Adverse Event Fatalities Related to GI Endoscopy.Digestive diseases and sciences · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Nosocomial outbreak linked to a flexible gastrointestinal endoscope contaminated with an amikacin-resistant ST17 clone of Pseudomonas aeruginosa.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020
    Article
  18. Detection of Carbapenem-Resistance Genes inAntibiotics (Basel, Switzerland) · 2020
    Article
  19. Clinical Questions and Answers on Gastrointestinal Endoscopy during the Novel Coronavirus Disease 2019 pandemic.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2020
    Review
  20. COVID-19 and gastrointestinal endoscopies: Current insights and emergent strategies.Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy Society · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

M Rubayat RahmanTexas Tech University, Lubbock, USA.
Abhilash PerisettiDepartment of Gastroenterology and Hepatology, University of Arkansas For Medical Sciences, Little Rock, AR, USA.
Roxana ComanGastroenterology Division, The Medical Center Navicent Health, 777 Hemlock St., Macon, GA, 31201, USA.
Pardeep BansalGI Fellowship Program, The Wright Center of Graduate Medical Education, Scranton, USA.
Rajiv ChhabraDepartment of Gastroenterology, University of Missouri Kansas City (UMKC) School of Medicine, Saint Luke's Hospital, 4321 Washington Street, Suite 5100, Kansas City, MO, 64111, USA.
Hemant GoyalMercer University School of Medicine, 707 Pine St, Macon, GA, 31201, USA. doc.hemant@yahoo.com.ORCID http://orcid.org/0000-0002-9433-9042

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The duodenoscope is among the most complex medical instruments that undergo disinfection between patients. Transmission of infection by contaminated scopes has remained a challenge since its inception. Notable risk factors for pathogen transmission include non-adherence to disinfection guidelines, encouragement of biofilm deposition due to complex design and surface defects and contaminated automated endoscope reprocessors. The most common infections following endoscopy are endogenous infections involving the patient's own gut flora. Exogenous infections, on the other hand, are associated with contaminated scopes and can theoretically be prevented by effective reprocessing. Pseudomonas aeruginosa is currently the most common organism isolated from contaminated endoscopes. Of note, reports of multidrug-resistant duodenoscopy-associated outbreaks have surfaced recently, many of which occurred despite adequate reprocessing. The FDA and CDC currently recommend comprehensive cleaning followed with at least high-level disinfection for reprocessing of flexible GI endoscopes. Reports of duodenoscope-related outbreaks despite compliance with established guidelines have prompted professional and government bodies to revisit existing guidelines and offer supplementary recommendations for duodenoscope processing. For the purposes of this review, we identified reports of duodenoscope-associated infections from 2000 till date. For each outbreak, we noted the organisms isolated, the number of cases reported, any possible explanations of contamination, and the measures undertaken to end each outbreak. We have also attempted to present an overview of recent developments in this rapidly evolving field.

Indexed as

Disease OutbreaksEquipment ContaminationGastrointestinal MicrobiomeAnti-Bacterial AgentsAntibiotic ProphylaxisBacterial InfectionsDecontaminationDuodenoscopesDuodenoscopyEquipment ReuseHumansRisk AssessmentRisk FactorsAnti-Bacterial AgentsContaminationDuodenoscopesEndoscopic retrograde cholangiopancreatographyInfection

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.