Evidence map›Paper›PMID 30569246›Full record

ArticleMikrochimica acta2018

A silver(I) doped bud-like DNA nanostructure as a dual-functional nanolabel for voltammetric discrimination of methylated from unmethylated genes.

Samaneh Hadian-Ghazvini, Hedayatollah Ghourchian, Shahram Agah, Ebrahim Ghafar-Zadeh

Abstract read
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Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Samaneh Hadian-GhazviniLaboratory of Bioanalysis, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, 1417614335, Iran.
Hedayatollah GhourchianLaboratory of Bioanalysis, Institute of Biochemistry and Biophysics, University of Tehran, Tehran, 1417614335, Iran. ghourchian@ut.ac.ir.
Shahram AgahColorectal Research Center, Iran University of Medical Sciences, Tehran, 1445613131, Iran.
Ebrahim Ghafar-ZadehBiologically Inspired Sensors and Actuators Laboratory, Department of Electrical Engineering and Computer Science, York University, Toronto, ON, M3J1P3, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A small DNA structure, referred to as DNA nanobud (NB), was used for the first time to design a dual-functional nanolabel in order to recognize a particular oligonucleotide sequence, generate and amplify the electrochemical analytical signal. NBs containing numerous repetitive desired sequences were prepared through self-assembly of 8-h rolling circle amplification. Then, redox-active silver ions were loaded onto the NBs by over-night incubation with a solution of AgNO

Indexed as

DNA MethylationBase SequenceBiosensing TechniquesBone Morphogenetic Protein 3DNAElectrochemical TechniquesGenesHumansMolecular ProbesNanostructuresNucleic Acid Amplification TechniquesOligonucleotidesSilverStaining and LabelingBMP3 protein, humanBone Morphogenetic Protein 3DNAMolecular ProbesOligonucleotidesSilverDNA-based nanostructureDNA methylation detectionElectrochemical labelRolling circle amplificationSignal amplification

Identifiers

PMID30569246

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.