Evidence map›Paper›PMID 30569231›Full record

ArticleMikrochimica acta2018

A split aptamer-labeled ratiometric fluorescent biosensor for specific detection of adenosine in human urine.

Junhui You, Zhengyi You, Xin Xu, Jiangrong Ji, Tian Lu, Yuhong Xia, Lipin Wang, Liying Zhang, Shuhu Du

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Junhui YouSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Zhengyi YouSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Xin XuSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Jiangrong JiSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Tian LuSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Yuhong XiaSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Lipin WangSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Liying ZhangSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China.
Shuhu DuSchool of Pharmacy, Nanjing Medical University, Nanjing, 211166, Jiangsu, China. shuhudu@njmu.edu.cn.
Nanjing Medical University · CN

Funding

National Natural Science Foundation of China 21775073National Natural Science Foundation of China 61605084Natural Science Research of Jiangsu Higher Education Institutions of China 16KJB150029Science and Technology Funds of Nanjing Medical University 2015NJMUZD023
6 · The paper itself

Abstract

A dual-emission ratiometric fluorometric aptasensor is presented for highly specific detection of adenosine. An adenosine binding aptamer (ABA) was split into two halves (termed as ABA1 and ABA2). ABA1 was covalently bound to blue-emitting carbon dots (with excitation/emission maxima at 365/440 nm) as responsive fluorophore (referred to as ABA1-CDs). ABA2 was linked to red-emitting silica-coated CdTe quantum dots (with excitation/emission maxima at 365/613 nm) acting as internal reference and referred to as ABA2-QDs@SiO

Indexed as

Aptamers, NucleotideFluorescenceAdenosineBiosensing TechniquesColorFluorescence Resonance Energy TransferHumansQuantum DotsAdenosineAptamers, NucleotideAdenosineCarbon dotsCdTe quantum dotsFluorescence resonance energy transferGraphene oxideNanoprobeVisual detection

Identifiers

PMID30569231
OpenAlexW2904933009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.