ReviewPflugers Archiv : European journal of physiology2019
Hibernating astronauts-science or fiction?
Review in Pflugers Archiv : European journal of physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 54 citations in OpenAlex.
- Using Organoids to Unlock the Potential of Human Torpor for Spaceflight.Current stem cell reports · 2026Article
- Discovering a low-dimensional temperature control architecture across animals.Scientific reports · 2026Article
- Induction and regulation of reversible suspended animation in C. elegans.Nature communications · 2026Article
- Induction and regulation of a reversible form of suspended animation inbioRxiv : the preprint server for biology · 2026Article
- Integrative focus on the space exposome-integrome: physiological challenges and practical limits of countermeasures beyond low Earth orbit.NPJ microgravity · 2025Review
- Mammalian birth versus arousal from hibernation: thyroid hormones, common regulators of metabolic transition?Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2025Review
- Review
- Multiple time points of transcriptome analysis revealed altered genes involved in maintaining hibernation in the hypothalamus ofFrontiers in neuroscience · 2024Article
- Multiorgan ultrastructural changes in rats induced in synthetic torpor.Frontiers in physiology · 2024Article
- Blood transcriptomics mirror regulatory mechanisms during hibernation-a comparative analysis of the Djungarian hamster with other mammalian species.Pflugers Archiv : European journal of physiology · 2023Article
- Energy and time optimization during exit from torpor in vertebrate endotherms.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2023Article
- Evaluation of deep space exploration risks and mitigations against radiation and microgravity.Frontiers in nuclear medicine · 2023Review
- Why bears hibernate? Redefining the scaling energetics of hibernation.Proceedings. Biological sciences · 2022Article
- Mitochondrial respiration in rats during hypothermia resulting from central drug administration.Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology · 2022Article
- Pediatric Hypothermia: An Ambiguous Issue.International journal of environmental research and public health · 2021Review
- Limits of temperature adaptation and thermopreferendum.Cell & bioscience · 2021Article
- Winter is coming: the future of cryopreservation.BMC biology · 2021Review
- Hibernation as a Tool for Radiation Protection in Space Exploration.Life (Basel, Switzerland) · 2021Review
- Body Temperature and Activity Adaptation of Short Photoperiod-Exposed Djungarian Hamsters (Frontiers in physiology · 2021Article
- Body Protein Sparing in Hibernators: A Source for Biomedical Innovation.Frontiers in physiology · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For long-duration manned space missions to Mars and beyond, reduction of astronaut metabolism by torpor, the metabolic state during hibernation of animals, would be a game changer: Water and food intake could be reduced by up to 75% and thus reducing payload of the spacecraft. Metabolic rate reduction in natural torpor is linked to profound changes in biochemical processes, i.e., shift from glycolysis to lipolysis and ketone utilization, intensive but reversible alterations in organs like the brain and kidney, and in heart rate control via Ca
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.