ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019
Flexible transnasal endoscopy with white light or narrow band imaging for the diagnosis of laryngeal malignancy: diagnostic value, observer variability and influence of previous laryngeal surgery.
Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Systematic Review Evaluating the Diagnostic Efficacy of Narrow-Band Imaging for Laryngeal Cancer Detection.Medicina (Kaunas, Lithuania) · 2024Pooled it
- Real-Time AI-Based Assessment of Glottic Lesions During Flexible Laryngoscopy: Comparison with Expert Evaluation and Histopathology.Medical sciences (Basel, Switzerland) · 2026Article
- Real-time AI-assisted quality control during nasopharyngolaryngoscopy: a randomized controlled trial.NPJ digital medicine · 2026Article
- Structured Early Follow-Up in Head and Neck Squamous Cell Carcinomas: A Retrospective Cohort Study.Biomedicines · 2025Article
- Laryngeal Carcinoma Characteristics Associated with Positive Margins and Endoscopic Understaging.Diagnostics (Basel, Switzerland) · 2025Article
- Correlation of Narrow Band Imaging Patterns with Histopathology Reports in Head and Neck Lesions.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- The influence of clinical experience on reliable evaluation of pharyngeal and laryngeal lesions: comparison of high-definition laryngoscopy using narrow band imaging with fibre-optic laryngoscopy.The Journal of laryngology and otology · 2024Article
- Head and Neck Squamous Cell Carcinoma of Unknown Primary: A Diagnostic Work-Up.The oncologist · 2024Article
- The Multimodal Diagnostic Approach Necessary in Detecting Elusive Submucosal Laryngeal Cancer.Cureus · 2023Article
- Artificial Intelligence in Laryngeal Endoscopy: Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- LPCANet: Classification of Laryngeal Cancer Histopathological Images Using a CNN with Position Attention and Channel Attention Mechanisms.Interdisciplinary sciences, computational life sciences · 2021Article
- The value of narrowband imaging using the Ni classification in the diagnosis of laryngeal cancer.Laryngoscope investigative otolaryngology · 2020Article
- Article
- Value of pre- and intraoperative diagnostic methods in suspected glottic neoplasia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
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4 authors.
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Abstract
purposeFlexible transnasal endoscopy is a common examination technique for the evaluation of laryngeal lesions, while the use of narrow band imaging (NBI) has been reported to enhance the diagnostic value of white light endoscopy (WLE). The purpose of this study is to assess observer variability and diagnostic value of both modalities and investigate the possible influence of previous laryngeal surgery on the detection rates of laryngeal malignancy.
methodsThe study was based on the retrospective evaluation of 170 WLE and NBI images of laryngeal lesions by three observers in a random order. The histopathological diagnoses serve as the gold standard.
resultsIn identifying laryngeal malignancy, the sensitivity of NBI proved to be higher than that of WLE (93.3% vs. 77.0%). NBI was also superior to WLE in terms of accuracy (96.3% vs. 92%) and diagnostic odds ratio (501.83 vs. 120.65). Both modalities had a specificity of 97.3%. The inter-observer agreement was substantial (kappa = 0.661) for WLE and almost perfect (kappa = 0.849) for NBI. Both WLE and NBI showed a high level of intra-observer agreement. The sensitivity was significantly lower in images with history of previous laryngeal surgery compared to those without.
conclusionsFlexible transnasal endoscopy has been proved to be a valuable tool in the diagnosis of laryngeal malignancy. The use of NBI can increase the sensitivity and observer reliability in that context and can also provide a diagnostic gain in cases with previous laryngeal surgery.
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