ArticleThe journal of prevention of Alzheimer's disease2019
Diet as a Risk Factor for Cognitive Decline in African Americans and Caucasians with a Parental History of Alzheimer's Disease: A Cross-Sectional Pilot Study Dietary Patterns.
Article in The journal of prevention of Alzheimer's disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.
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Who cites it
14 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Effect of nutrition in Alzheimer's disease: A systematic review.Frontiers in neuroscience · 2023Pooled it
- Blood pressure and Alzheimer's disease: A review of meta-analysis.Frontiers in neurology · 2022Pooled it
- Overcoming Racial/Ethnic Disparities in Alzheimer Disease and Related Dementias: Time for a Closer Look.JACC. Advances · 2024Article
- Alzheimer's disease: a comprehensive review of epidemiology, risk factors, symptoms diagnosis, management, caregiving, advanced treatments and associated challenges.Frontiers in medicine · 2024Review
- Alzheimer's Disease and Alzheimer's Disease-Related Dementias in African Americans: Focus on Caregivers.Healthcare (Basel, Switzerland) · 2023Review
- Somatic comorbidity and the progression of cognitive impairment.Frontiers in aging neuroscience · 2023Article
- Article
- A healthy plant-based diet was associated with slower cognitive decline in African American older adults: a biracial community-based cohort.The American journal of clinical nutrition · 2022Article
- Microbial-derived metabolites as a risk factor of age-related cognitive decline and dementia.Molecular neurodegeneration · 2022Review
- Manipulation of the diet-microbiota-brain axis in Alzheimer's disease.Frontiers in neuroscience · 2022Review
- Lifestyle Factors Influencing Dietary Patterns of University Professors.International journal of environmental research and public health · 2021Observational
- A Pilot randomized clinical trial of adapted tango to improve cognition and psychosocial function in African American women with family history of Alzheimer's disease (ACT trial).Cerebral circulation - cognition and behavior · 2021Article
- Longitudinal associations between dietary quality and Alzheimer's disease genetic risk on cognitive performance among African American adults.The British journal of nutrition · 2020Article
- Pilot: Salivary lactoferrin as a potential preclinical Alzheimer's disease biomarker.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundAfrican Americans (AA) are more likely to develop Alzheimer's disease (AD) than Caucasians (CC). Dietary modification may have the potential to reduce the risk of developing AD.
objectiveThe objective of this study is to investigate the relationship between Southern and Prudent diet patterns and cognitive performance in individuals at risk for developing AD.
designCross-sectional observational study.
participantsSixty-six cognitively normal AA and CC individuals aged 46-77 years with a parental history of AD were enrolled. MEASUREMENTS: Participants completed a Food Frequency questionnaire, cognitive function testing, which consisted of 8 neuropsychological tests, and cardiovascular risk factor assessments, including evaluation of microvascular and macrovascular function and ambulatory blood pressure monitoring.
resultsResults revealed a relationship between the Southern diet and worse cognitive performance among AAs. AAs who consumed pies, mashed potatoes, tea, and sugar drinks showed worse cognitive performance (p<0.05) compared with CCs. In addition, gravy (p=0.06) and cooking oil/fat (p=0.06) showed negative trends with cognitive performance in AAs. In both CC and AA adults, greater adherence to a Prudent dietary pattern was associated with better cognitive outcomes. Cardiovascular results show that participants are overall healthy. AAs and CCs did not differ on any vascular measure including BP, arterial stiffness and endothelial function.
conclusionResearch shows that dietary factors can associate with cognitive outcomes. This preliminary cross-sectional study suggests that foods characteristic of the Southern and Prudent diets may have differential effects on cognitive function in middle-aged individuals at high risk for AD. Results suggest that diet could be a non-pharmaceutical tool to reduce cognitive decline in racially diverse populations. It is possible that the increased prevalence of AD in AA could be partially reduced via diet modification.
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