Evidence map›Paper›PMID 30568984›Full record

ArticleOpen forum infectious diseases2018

Human Immunodeficiency Virus-1 Drug Resistance Patterns Among Adult Patients Failing Second-Line Protease Inhibitor-Containing Regimens in Namibia, 2010-2015.

Souleymane Sawadogo, Andreas Shiningavamwe, Clay Roscoe, Andrew L Baughman, Taffa Negussie, Gram Mutandi, Chunfu Yang, Ndapewa Hamunime, Simon Agolory

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Souleymane SawadogoDivision of Global HIV and Tuberculosis, Windhoek, Namibia.
Andreas ShiningavamweNamibia Institute of Pathology, Windhoek.
Clay RoscoeDivision of Global HIV and Tuberculosis, Windhoek, Namibia.
Andrew L BaughmanDivision of Global HIV and Tuberculosis, Windhoek, Namibia.
Taffa NegussieDivision of Global HIV and Tuberculosis, Windhoek, Namibia.
Gram MutandiDivision of Global HIV and Tuberculosis, Windhoek, Namibia.
Chunfu YangDivision of Global HIV and Tuberculosis, Atlanta, Georgia.
Ndapewa HamunimeMinistry of Health and Social Services, Windhoek, Namibia.
Simon AgoloryDivision of Global HIV and Tuberculosis, Windhoek, Namibia.

Funding

NCHHSTP CDC HHS U2G PS002058
6 · The paper itself

Abstract

Three hundred sixty-six adult patients in Namibia with second-line virologic failures were evaluated for human immunodeficiency virus drug-resistant (HIVDR) mutations. Less than half (41.5%) harbored ≥1 HIVDR mutations to standardized second-line antiretroviral therapy (ART) regimen. Optimizing adherence, viral load monitoring, and genotyping are critical to prevent emergence of resistance, as well as unnecessary switching to costly third-line ART regimens.

Indexed as

ARTdrug resistanceNamibiasecond line

Identifiers

PMID30568984
PMCPMC5798139

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.