ArticleOpen forum infectious diseases2018
Risk Factors for Septicemia Deaths and Disparities in a Longitudinal US Cohort.
Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Observational
- A Research Agenda to Mitigate Racial and Ethnic Disparities in U.S. Critical Care Medicine: An Official American Thoracic Society Research Statement.American journal of respiratory and critical care medicine · 2025Article
- Frailty as an Independent Predictor of Mortality in Patients with Sepsis.Journal of personalized medicine · 2025Article
- The Relation Between Cigarette Smoking and Development of Sepsis: A 10-Year Follow-Up Study of Four Million Adults from the National Health Screening Program.Journal of epidemiology and global health · 2024Article
- Trajectories of State-Level Sepsis-Related Mortality by Race and Ethnicity Group in the United States.Journal of clinical medicine · 2024Article
- Proteomic changes associated with racial background and sepsis survival outcomes.Molecular omics · 2022Article
- Association between smoking and risk of death in patients with sepsis: A systematic review and meta-analysis.Tobacco induced diseases · 2022Review
- Evidence for an Inherited Contribution to Sepsis Susceptibility Among a Cohort of U.S. Veterans.Critical care explorations · 2022Article
- National Disparities in COVID-19 Outcomes between Black and White Americans.Journal of the National Medical Association · 2021Article
- Physician documentation matters. Using natural language processing to predict mortality in sepsis.Intelligence-based medicine · 2021Article
- Racial Disparities in Incidence of Legionnaires' Disease and Social Determinants of Health: A Narrative Review.Public health reports (Washington, D.C. : 1974)Review
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Authors and funding
4 authors.
Funding
Abstract
backgroundThere are few longitudinal data on the risk factors and mediators of racial disparities in sepsis among community- dwelling US adults.
methodsThis is a longitudinal study of adult participants in the 1999-2005 National Health Interview Survey with data linked to the 1999-2011 National Death Index. We utilized National Vital Statistics System's ICD-10 schema to define septicemia deaths (A40-A41), utilizing influenza and pneumonia deaths (J09-J11) and other causes of death as descriptive comparators. All statistics utilized survey design variables to approximate the US adult population.
resultsOf 206 691 adult survey participants, 1523 experienced a septicemia death. Factors associated with a >2-fold larger hazard of septicemia death included need for help with activities of daily living; self-reported "poor" and "fair" general health; lower education; lower poverty index ratio; self-reported emphysema, liver condition, stroke, and weak or failing kidneys; numerous measures of disability; general health worse than the year prior; >1 pack per day cigarette use; and higher utilization of health care. Blacks had age- and sex-adjusted hazards that were higher for septicemia deaths (hazard ratio [HR], 1.92; 95% confidence interval [CI], 1.65-2.23) than for other causes of death (HR, 1.32; 95% CI, 1.25-1.38). The strongest mediators of the septicemia disparity included self-reported general health condition, family income-poverty ratio, and highest education level achieved.
conclusionsIn this cohort, the major risk factors for septicemia death were similar to those for other causes of death, there was approximately a 2-fold black-white disparity in septicemia deaths, and the strongest mediators of this disparity were across domains of socioeconomic status.
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