Evidence map›Paper›PMID 30568921›Full record

ArticleFrontiers in cellular and infection microbiology2018

Discovery of Antiamebic Compounds That Inhibit Cysteine Synthase From the Enteric Parasitic Protist

Mihoko Mori, Satoshi Tsuge, Wataru Fukasawa, Ghulam Jeelani, Kumiko Nakada-Tsukui, Kenichi Nonaka, Atsuko Matsumoto, Satoshi Ōmura, Tomoyoshi Nozaki, Kazuro Shiomi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Microbiology spectrum · 2025
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Progress in the Chemistry of Cytochalasans.Progress in the chemistry of organic natural products · 2021
    Article
  8. Revisiting Drug Development Against the Neglected Tropical Disease, Amebiasis.Frontiers in cellular and infection microbiology · 2020
    Review
  9. Bioactivities and Future Perspectives of Chaetoglobosins.Evidence-based complementary and alternative medicine : eCAM · 2020
    Review
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Mihoko MoriGraduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Satoshi TsugeGraduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Wataru FukasawaGraduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Ghulam JeelaniGraduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kumiko Nakada-TsukuiDepartment of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan.
Kenichi NonakaGraduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Atsuko MatsumotoGraduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Satoshi ŌmuraKitasato Institute for Life Sciences, Kitasato University, Tokyo, Japan.
Tomoyoshi NozakiGraduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Kazuro ShiomiGraduate School of Infection Control Sciences, Kitasato University, Tokyo, Japan.
Kitasato University · JPThe University of Tokyo · JPKitasato Institute Hospital · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amebiasis is caused by infection with the protozoan parasite

Indexed as

AmebiasisAntiprotozoal AgentsBiosynthetic PathwaysCell LineCysteineCysteine SynthaseDrug DiscoveryDrug Evaluation, PreclinicalEntamoeba histolyticaFibroblastsHumansOxidation-ReductionSecondary MetabolismTrophozoitesAntiprotozoal AgentsCysteineCysteine Synthaseamebiasisantiamebic compoundscysteine synthaseEntamoeba histolyticamicrobial secondary metabolitesnatural products

Identifiers

PMID30568921
PMCPMC6290340
OpenAlexW2903187591

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.