Evidence map›Paper›PMID 30568790›Full record

ArticleAntimicrobial resistance and infection control2018

Hydrogen peroxide and sodium hypochlorite disinfectants are more effective against

Caitlinn B Lineback, Carine A Nkemngong, Sophie Tongyu Wu, Xiaobao Li, Peter J Teska, Haley F Oliver

Open access · goldAbstract read
In one paragraph

Article in Antimicrobial resistance and infection control, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 182 citations in OpenAlex.

  1. Photodynamic anti-biofilm PHEMA/Rose Bengal hydrogels enhanced by iodide: evidence for hydrogen peroxide and triiodide formation.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
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  3. Temperature-dependent reprogramming of virulence traits duringbioRxiv : the preprint server for biology · 2026
    Article
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  8. Applied and environmental microbiology · 2026
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  11. Factors governing the response ofFrontiers in cellular and infection microbiology · 2026
    Review
  12. Effects of common disinfectants on biofilm formation and eradication inFrontiers in cellular and infection microbiology · 2026
    Article
  13. Polypropylene wiping cloths contaminated withAntimicrobial stewardship & healthcare epidemiology : ASHE · 2026
    Article
  14. Review
  15. Review
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  20. Review

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Caitlinn B Lineback1Department of Food Science, Purdue University, 745 Agriculture Mall Drive, West Lafayette, IN 47907 USA.
Carine A Nkemngong1Department of Food Science, Purdue University, 745 Agriculture Mall Drive, West Lafayette, IN 47907 USA.
Sophie Tongyu Wu1Department of Food Science, Purdue University, 745 Agriculture Mall Drive, West Lafayette, IN 47907 USA.
Xiaobao Li2Diversey Inc., Charlotte, NC 28273 USA.
Peter J Teska2Diversey Inc., Charlotte, NC 28273 USA.
Haley F Oliver1Department of Food Science, Purdue University, 745 Agriculture Mall Drive, West Lafayette, IN 47907 USA.ORCID 0000-0002-5851-6523
Purdue University West Lafayette · USUniversity of North Carolina at Charlotte · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Antimicrobial disinfectants are used as primary treatment options against pathogens on surfaces in healthcare facilities to help prevent healthcare associated infections (HAIs). On many surfaces, pathogenic microorganisms exist as biofilms and form an extracellular matrix that protects them from the antimicrobial effects of disinfectants. Disinfectants are used as all-purpose antimicrobials though very few specifically make biofilm efficacy claims. The objective of this study was to evaluate the efficacy of eight registered disinfectants (six registered by the Environmental Protection Agency and two products registered in by the European Chemical Agency) with general bactericidal claims, but currently no biofilm efficacy claims, against Methods: This study tested the bactericidal efficacy of eight registered disinfectant products against Results: Overall, sodium hypochlorite and hydrogen peroxide disinfectants had significantly higher bactericidal efficacies than quaternary ammonium chloride disinfectants. We also found that all tested disinfectants except for quaternary ammonium chloride disinfectants met and exceeded the EPA standard for bactericidal efficacy against biofilms. Conclusion: In general, bactericidal efficacy against biofilms differed by active ingredient. The efficacies of sodium hypochlorite and hydrogen peroxide disinfectants did not vary between strains, but there were significant differences between strains treated with quaternary ammonium chloride disinfectants.

Indexed as

Anti-Bacterial AgentsBiofilmsCross InfectionDisinfectantsDrug CombinationsDrug SynergismHydrogen PeroxidePseudomonas aeruginosaQuaternary Ammonium CompoundsSodium HypochloriteStaphylococcus aureusSurface PropertiesAnti-Bacterial AgentsDisinfectantsDrug CombinationsHydrogen PeroxideQuaternary Ammonium CompoundsSodium HypochloriteBiofilmsDisinfectantEfficacy

Identifiers

PMID30568790
PMCPMC6298007
OpenAlexW2904528716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.