ArticleIrish veterinary journal2018
Effects of midazolam on cardiovascular responses and isoflurane requirement during elective ovariohysterectomy in dogs.
Article in Irish veterinary journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 21 citations in OpenAlex.
- Case Report: Anesthetic management of two dogs with third-degree atrioventricular block undergoing elective non-cardiac surgery under temporary transvenous pacing.Frontiers in veterinary science · 2026Article
- Anaesthetic management and clinical outcomes of balloon pulmonary valvuloplasty in dogs with severe pulmonic stenosis: a retrospective study (2024-2025).Frontiers in veterinary science · 2026Article
- Intraoperative magnesium sulphate as an analgesic adjunct in a multimodal, opioid-sparing protocol for canine ovariohysterectomy: a prospective, randomized, controlled, double-blind study.Frontiers in veterinary science · 2026Article
- A Comparison of Two Different Methods for Inducing Apnoea During Thoracic Computed Tomography of Dogs.Animals : an open access journal from MDPI · 2025Article
- An Overview of Anesthetic Procedures for Ferret (Mustela putorius furo) Preclinical Brain MRI: A Call for Standardization.Journal of the American Association for Laboratory Animal Science : JAALAS · 2025Review
- Effects of ketamine, propofol and isoflurane on electrocardiographic variables in clinically healthy dogs premedicated with medetomidine and midazolam.Veterinary research forum : an international quarterly journal · 2024Article
- Nerve stimulator-guided mandibular block in an alpaca undergoing dental extraction.The Canadian veterinary journal = La revue veterinaire canadienne · 2023Article
- A comparison of intra and postoperative analgesic effects of sacrococcygeal and lumbosacral epidural levobupivacaine in cats undergoing ovariohysterectomy.The Journal of veterinary medical science · 2023Article
- Variation of rectal temperature in dogs undergoing 3T-MRI in general anesthesia.Frontiers in veterinary science · 2023Article
- Effects of Cisatracurium in Sevoflurane and Propofol Requirements in Dog-Undergoing-Mastectomy Surgery.Animals : an open access journal from MDPI · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA prospective, randomized, placebo-controlled, blinded clinical study was conducted to determine whether a single dose of midazolam affects the cardiovascular response to surgical manipulation of the ovaries during elective ovariohysterectomy. Thirty-nine client-owned dogs undergoing elective ovariohysterectomy were recruited. After scoring cage demeanour, dogs were premedicated with acepromazine (0.03 mg kg
resultsA statistical significant difference between groups was detected in FE'Iso, with group M requiring a significantly lower FE'Iso than group P (14.3%) after administration of midazolam. No differences between groups was shown for percentage change in heart rate and mean arterial blood pressure, or end-tidal carbon dioxide and requirement for mechanical ventilation, or rescue analgesia. There was no statistically significant difference in the incidence of complications in group M and P. Group M received significantly more succinylated gelatin solution pre-administration of midazolam than group P, but no differences in fluid administration post-administration of the study treatment (midazolam/placebo) were detected. No statistical significant difference was demonstrated for the use of anticholinergic agents, dobutamine or noradrenaline.
conclusionNo significant effect on cardiovascular parameters could be observed with administration of midazolam, but a modest (14.3%) isoflurane-sparing effect was detected.
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