Evidence map›Paper›PMID 30568602›Full record

ArticleFrontiers in physiology2018

Blockade of the Adenosine 2A Receptor Mitigates the Cardiomyopathy Induced by Loss of Plakophilin-2 Expression.

Marina Cerrone, Chantal J M van Opbergen, Kabir Malkani, Natasha Irrera, Mingliang Zhang, Toon A B Van Veen, Bruce Cronstein, Mario Delmar

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 13 citations in OpenAlex.

  1. Disease models and AAV therapies ofMolecular therapy. Advances · 2026
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  10. Disruption of CaCirculation · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Marina CerroneLeon H. Charney Division of Cardiology, NYU School of Medicine, New York, NY, United States.
Chantal J M van OpbergenDepartment of Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands.
Kabir MalkaniLeon H. Charney Division of Cardiology, NYU School of Medicine, New York, NY, United States.
Natasha IrreraDivision of Translational Medicine, NYU School of Medicine, New York, NY, United States.
Mingliang ZhangLeon H. Charney Division of Cardiology, NYU School of Medicine, New York, NY, United States.
Toon A B Van VeenDepartment of Medical Physiology, Division of Heart and Lungs, University Medical Center Utrecht, Utrecht, Netherlands.
Bruce CronsteinDivision of Translational Medicine, NYU School of Medicine, New York, NY, United States.
Mario DelmarLeon H. Charney Division of Cardiology, NYU School of Medicine, New York, NY, United States.
New York University · USUniversity Medical Center Utrecht · NLUniversity of Messina · IT

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2012 to 2014
$16.8M
PH REGULATION OF CONNEXIN43--INTERMEDIARY STEPSR01GM057691 · NIGMS · UPSTATE MEDICAL UNIVERSITY · PI DELMAR, MARIO · 1999 to 2016
$5.6M
The Pharmacology of Dermal Fibrosis R01AR056672 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL · 2009 to 2018
$4.6M
Role of PKP2 in epicardial structure and functionR01HL136179 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO, MORLEY, GREGORY E · 2017 to 2020
$3.1M
Purinergic Stimulation of Bone RegenerationR01AR068593 · NIAMS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI COELHO, PAULO G, CRONSTEIN, BRUCE NEIL · 2015 to 2019
$2.8M
Role of desmosomes in cardiac electrical functionR01HL134328 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI DELMAR, MARIO, MORLEY, GREGORY E · 2016 to 2019
$2.6M
NCATS NIH HHS UL1 TR000038NCATS NIH HHS UL1 TR001445NHLBI NIH HHS R01 HL134328NHLBI NIH HHS R01 HL136179NIAMS NIH HHS R01 AR056672NIAMS NIH HHS R01 AR068593NIGMS NIH HHS R01 GM057691
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

adenosinearrhythmogenic right ventricular cardiomyopathyATPcardiomyopathydesmosomesfibrosismouse models of arrhythmiasplakophilin-2

Identifiers

PMID30568602
PMCPMC6290386
OpenAlexW2902139314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.