Evidence map›Paper›PMID 30568504›Full record

ArticleCancer management and research2018

NLRP6, decreased in gastric cancer, suppresses tumorigenicity of gastric cancer cells.

Qingqing Wang, Chunmei Wang, Jinlian Chen

Open access · goldAbstract read
In one paragraph

Article in Cancer management and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 38 citations in OpenAlex.

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  10. The latest breakthrough on NLRP6 inflammasome.Precision clinical medicine · 2022
    Review
  11. Article
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  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Qingqing WangDepartment of Gastroenterology, Fengxian Hospital, Anhui University of Science and Technology, Shanghai 201499, China.
Chunmei WangDepartment of Gastroenterology, Fengxian Hospital, Southern Medical University, Shanghai 201499, China, wqq_021002@163.com.
Jinlian ChenDepartment of Gastroenterology, Fengxian Hospital, Southern Medical University, Shanghai 201499, China, wqq_021002@163.com.
Shanghai Sixth People's Hospital · CNAnhui University of Science and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMATERIALS AND

methodsWe examined NLRP6 expression in gastric cancer and adjacent normal gastric tissues. The biological functions and mechanism of NLRP6 overexpression in gastric cancer cells were investigated.

resultsDownregulated NLRP6 expression in human gastric cancer significantly correlated with

conclusionOur study may provide insight into the understanding of NLRP6 as a tumor suppressor and implicate the potential application of NLRP6 for gastric cancer treatment.

Indexed as

cell apoptosiscell proliferationgastric cancerH. pyloriNLRP6

Identifiers

PMID30568504
PMCPMC6267737
OpenAlexW2903343344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.