Evidence map›Paper›PMID 30568461›Full record

ArticleOncoTargets and therapy2018

Prognostic roles of mRNA expression of peroxiredoxins in lung cancer.

Liangyuan Chen, Chunli Huang, Xiaojun Yang, Qiuqin Zhang, Falin Chen

Open access · goldAbstract read
In one paragraph

Article in OncoTargets and therapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Role of Different Enzymes in HInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. The Role of Peroxiredoxin Family in Cancer Signaling.Journal of cancer prevention · 2019
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Liangyuan ChenDepartment of Clinical Laboratory, Fujian Provincial Hospital, Fuzhou, People's Republic of China, chenfalin008@126.com.
Chunli HuangDepartment of Clinical Laboratory, Fujian Provincial Hospital, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, People's Republic of China, chenfalin008@126.com.
Xiaojun YangDepartment of Transfusion Medicine, Shengli Clinical Medical College of Fujian Medical University, Fuzhou, People's Republic of China.
Qiuqin ZhangDepartment of Clinical Laboratory, Fujian Provincial Hospital, Fuzhou, People's Republic of China, chenfalin008@126.com.
Falin ChenDepartment of Clinical Laboratory, Fujian Provincial Hospital, Fuzhou, People's Republic of China, chenfalin008@126.com.
Fujian Medical University · CNFujian Provincial People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe peroxiredoxin (PRDX) protein family is involved in cancer cell invasion and metastasis, but its prognostic value in lung cancer remain elusive.

methodsIn this report, we accessed the overall survival (OS) of each individual

resultsOur results indicated that

conclusionOur finding will elucidate the prognostic role of PRDXs in lung cancer and might promote development of PRDX-targeted inhibitors for the treatment of lung cancer.

Indexed as

expressionKM plotterlung cancerPRDXprognosticsmoking status

Identifiers

PMID30568461
PMCPMC6267628
OpenAlexW2903141364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.