Evidence map›Paper›PMID 30568441›Full record

ArticleInternational journal of nanomedicine2018

Silica-gentamicin nanohybrids: combating antibiotic resistance, bacterial biofilms, and in vivo toxicity.

Dina A Mosselhy, Wei He, Ulla Hynönen, Yaping Meng, Pezhman Mohammadi, Airi Palva, Qingling Feng, Simo-Pekka Hannula, Katrina Nordström, Markus B Linder

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 23 citations in OpenAlex.

  1. Advances in Nanostructures for Antimicrobial Therapy.Materials (Basel, Switzerland) · 2022
    Review
  2. Article
  3. Article
  4. Review
  5. Nanobiosystems for Antimicrobial Drug-Resistant Infections.Nanomaterials (Basel, Switzerland) · 2021
    Review
  6. Article
  7. [Application of nanodrug carriers in the prevention and treatment of infection around orthopedic prosthesis].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2019
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 4 countries.

Dina A MosselhyDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Espoo, Finland, dina.mosselhy@aalto.fi.
Wei HeSchool of Materials Science and Engineering, University of Science and Technology Beijing, Beijing, People's Republic of China.
Ulla HynönenDepartment of Veterinary Biosciences, Division of Veterinary Microbiology and Epidemiology, University of Helsinki, Helsinki, Finland.
Yaping MengState Key Laboratory of Biomembrane and Membrane Biotechnology, Department of Biological Sciences and Biotechnology, Tsinghua University, Beijing, People's Republic of China.
Pezhman MohammadiDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Espoo, Finland, dina.mosselhy@aalto.fi.
Airi PalvaDepartment of Veterinary Biosciences, Division of Veterinary Microbiology and Epidemiology, University of Helsinki, Helsinki, Finland.
Qingling FengState Key Laboratory of New Ceramics and Fine Processing, School of Materials Science and Engineering, Tsinghua University, Beijing, People's Republic of China, biomater@mail.tsinghua.edu.cn.
Simo-Pekka HannulaDepartment of Chemistry and Materials Science, School of Chemical Engineering, Aalto University, Espoo, Finland, dina.mosselhy@aalto.fi.
Katrina NordströmDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Espoo, Finland, dina.mosselhy@aalto.fi.
Markus B LinderDepartment of Bioproducts and Biosystems, School of Chemical Engineering, Aalto University, Espoo, Finland, dina.mosselhy@aalto.fi.
Aalto University · FIUniversity of Helsinki · FINational Bioproducts Institute (South Africa) · ZAState Key Laboratory of New Ceramics and Fine ProcessingTsinghua University · CNUniversity of Science and Technology Beijing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntibiotic resistance is a growing concern in health care. Methicillin-resistant MATERIALS AND

methodsIn this work, we have investigated the effects of SiO

resultsSiO

conclusionCollectively, this work provides the first comprehensive in vivo assessment of SiO

Indexed as

Toxicity TestsAnimalsAnti-Bacterial AgentsBiofilmsDrug Resistance, BacterialEmbryo, NonmammalianEscherichia coliGentamicinsHumansLarvaMethicillin-Resistant Staphylococcus aureusMicrobial Sensitivity TestsNanoparticlesSilicon DioxideZebrafishAnti-Bacterial AgentsGentamicinsSilicon Dioxideantibacterial and antibiofilm effectsgentamicinMRSAnanotoxicitySiO2zebrafish

Identifiers

PMID30568441
PMCPMC6276608
OpenAlexW2902524197

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.