ArticleInternational journal of chronic obstructive pulmonary disease
Influence of comorbid heart disease on dyspnea and health status in patients with COPD - a cohort study.
Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 11 citations in OpenAlex.
- Comorbid asthma - occurrence and associations with patient-related outcomes in COPD: a cohort study.Scandinavian journal of primary health care · 2027Article
- Determinants of poor chronic obstructive pulmonary disease control.The Libyan journal of medicine · 2025Article
- Impact of Cardiovascular and Metabolic Comorbidities on Long-term Outcomes of Home-based Pulmonary Rehabilitation in COPD.International journal of chronic obstructive pulmonary disease · 2023Article
- Applying the Rome Proposal on Exacerbations of Chronic Obstructive Pulmonary Disease: Does Comorbid Chronic Heart Failure Matter?International journal of chronic obstructive pulmonary disease · 2023Article
- Distribution of COPD Comorbidities and Creation of Acute Exacerbation Risk Score: Results from SCICP.Journal of inflammation research · 2021Article
- Clinical Development and Research Applications of the Chronic Obstructive Pulmonary Disease Assessment Test.American journal of respiratory and critical care medicine · 2020Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to examine the changing influence over time of comorbid heart disease on symptoms and health status in patients with COPD. PATIENTS AND
methodsThis is a prospective cohort study of 495 COPD patients with a baseline in 2005 and follow-up in 2012. The study population was divided into three groups: patients without heart disease (no-HD), those diagnosed with heart disease during the study period (new-HD) and those with heart disease at baseline (HD). Symptoms were measured using the mMRC. Health status was measured using the Clinical COPD Questionnaire (CCQ) and the COPD Assessment Test (CAT; only available in 2012). Logistic regression with mMRC ≥2 and linear regression with CCQ and CAT scores in 2012 as dependent variables were performed unadjusted, adjusted for potential confounders, and additionally adjusted for baseline mMRC, respectively, CCQ scores.
resultsMean mMRC worsened from 2005 to 2012 as follows: for the no-HD group from 1.8 (±1.3) to 2.0 (±1.4), (
conclusionHeart disease contributes to lower health status and higher symptom burden in COPD but does not accelerate the worsening over time.
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Registered trials
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