ArticleNeurologia medico-chirurgica2019
Effects of Hemosiderosis on Epilepsy Following Subarachnoid Hemorrhage.
Article in Neurologia medico-chirurgica, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Incidence of Early and In-hospital Late Seizures Following Aneurysmal Subarachnoid Hemorrhage in Patients Treated with Clazosentan: A Multicenter Retrospective Cohort Study.Neurologia medico-chirurgica · 2026Article
- In Vivo Longitudinal Mapping of Brain Iron Accumulation After Pilocarpine-Induced Status Epilepticus.Molecular neurobiology · 2026Article
- Neuroprotective Effects of the Nonsteroidal Anti-inflammatory Drug Celecoxib Against Caspase-1-dependent Pyroptosis Partially by Suppressing the HMGB1/TLR4 Pathway.Cellular and molecular neurobiology · 2025Article
- Classical type of superficial hemosiderosis presenting with temporal lobe epilepsy.Surgical neurology international · 2025Article
- Impact of age on surgical outcomes for world federation of neurosurgical societies grade I and II aneurysmal subarachnoid haemorrhage: a novel prognostic model using recursive partitioning analysis.Neurosurgical review · 2024Article
- The hidden link between late-onset seizures and cerebral amyloid angiopathy: A case-control study.Epilepsia open · 2024Observational
- Pathophysiology, Diagnosis, Prognosis, and Prevention of Poststroke Epilepsy: Clinical and Research Implications.Neurology · 2024Review
- The Progress of Poststroke Seizures.Neurochemical research · 2024Review
- Factors Associated with Early and Late Seizure Related to Aneurysmal Subarachnoid Hemorrhage.Neurologia medico-chirurgica · 2024Article
- Association of Cortical Superficial Siderosis with Post-Stroke Epilepsy.Annals of neurology · 2023Article
- Identification of hub genes significantly linked to subarachnoid hemorrhage and epilepsyFrontiers in neurology · 2023Article
- Risk factors for early seizure after revascularization in patients with moyamoya disease.Chinese neurosurgical journal · 2022Article
- Factors Associated with Prolonged Impairment of Consciousness in Adult Patients Admitted for Seizures: A Comprehensive Single-center Study.Neurologia medico-chirurgica · 2021Article
- Emerging Role of Microglia-Mediated Neuroinflammation in Epilepsy after Subarachnoid Hemorrhage.Molecular neurobiology · 2021Review
- Pitfalls of Commonly Used Ischemic and Dementia Models Due to Early Seizure by Carotid Ligation.Neurologia medico-chirurgica · 2021Article
- Case Report: Late-Onset Temporal Lobe Epilepsy Following Subarachnoid Hemorrhage: An Interplay Between Pre-existing Cortical Development Abnormality and Tissue Damage.Frontiers in neurology · 2021Article
- Far-anterior Interhemispheric Transcallosal Approach for a Central Neurocytoma in the Lateral Ventricle.Neurologia medico-chirurgica · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Epilepsy after aneurysmal subarachnoid hemorrhage (post-SAH epilepsy) is a critical complication that influences clinical and social prognoses. However, the underlying mechanisms remain unclear. We investigated the relationship between hemosiderosis and the incidence of post-SAH epilepsy. About 50 patients with aneurysmal SAH who were admitted to Sapporo Medical University and Oji General Hospital between April 2010 and June 2016 were enrolled in this retrospective study. Hemosiderosis detected by T2*-weighted magnetic resonance imaging(MRI) and the incidence of post-SAH epilepsy were retrospectively analyzed. Post-SAH epilepsy was defined as an unprovoked seizures occurring more than 1 week after the onset of SAH. Six patients (12%) developed post-SAH epilepsy. In all patients, hemosiderosis in the cortex or cerebral parenchyma was detected by T2*-weighted MRI. Statistical analyses revealed that hemosiderosis and the co-existence of intracerebral hemorrhage (ICH) related with post-SAH epilepsy (Fisher's exact test, univariate exact logistic regression analysis: P < 0.05). Post-SAH epilepsy was predicted by hemosiderosis and the co-existence of ICH. The present results suggest that hemosiderin is the principal cause of post-SAH epilepsy and may be a predictor of this critical complication.
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