ArticleGenes & development2019
Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination.
Erratum issuedOpen access · diamondAbstract read
In one paragraph
Article in Genes & development, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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12citing papers in PubMed
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What it found
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Who cites it
12 citing papers in PubMed, 24 citations in OpenAlex.
- hnRNPA2B1 deacetylation by SIRT6 restrains local transcription and safeguards genome stability.Cell death and differentiation · 2025Article
- ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway.Nature communications · 2024Article
- ZNF432 stimulates PARylation and inhibits DNA resection to balance PARPi sensitivity and resistance.Nucleic acids research · 2023Article
- Zinc finger protein 280C contributes to colorectal tumorigenesis by maintaining epigenetic repression at H3K27me3-marked loci.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- DNA repair defects in cancer and therapeutic opportunities.Genes & development · 2022Review
- Translesion DNA synthesis-driven mutagenesis in very early embryogenesis of fast cleaving embryos.Nucleic acids research · 2022Article
- POGZ promotes homology-directed DNA repair in an HP1-dependent manner.EMBO reports · 2022Article
- DNA Repair Pathway Choices in CRISPR-Cas9-Mediated Genome Editing.Trends in genetics : TIG · 2021Review
- Article
- Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress.International journal of molecular sciences · 2021Review
- Zinc finger protein E4F1 cooperates with PARP-1 and BRG1 to promote DNA double-strand break repair.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Recent advancements in PARP inhibitors-based targeted cancer therapy.Precision clinical medicine · 2020Review
Corrections and comments
- Erratum issued
Authors and funding
14 authors at 3 institutions in 2 countries.
David M MoquinMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Marie-Michelle Genois *Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Jia-Min Zhang *Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Jian Ouyang *Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Tribhuwan Yadav *Massachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Rémi BuissonMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Stephanie A YazinskiMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Jun TanMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Myriam BoukhaliMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Jean-Philippe GagnéCentre de Recherche du CHU de Quebec, Laval University, Quebec, Quebec G1V 4G2, Canada.
Guy G PoirierCentre de Recherche du CHU de Quebec, Laval University, Quebec, Quebec G1V 4G2, Canada.
Li LanMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Wilhelm HaasMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Lee ZouMassachusetts General Hospital Cancer Center, Harvard Medical School, Charlestown, Massachusetts 02129, USA.
Harvard University · USMassachusetts General Hospital · USUniversité Laval · CA
Funding
Regulation of the ATR Checkpoint Kinase by DNA DamageR01GM076388 · NIGMS · MASSACHUSETTS GENERAL HOSPITAL · PI ZOU, LEE · 2006 to 2018
$4.3MImplications of the ATR Checkpoint Kinase in Radiation and Targeted TherapiesR01CA197779 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI ZOU, LEE · 2015 to 2020
$2.4MTranscription-Coupled Homologous Recombination upon DNA DamageR01GM118833 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LAN, LI · 2016 to 2020
$1.6MTARGETING APOBEC3A-EXPRESSING CANCER CELLS WITH ATR INHIBITORSR00CA212154 · NCI · UNIVERSITY OF CALIFORNIA-IRVINE · PI BUISSON, REMI · 2018 to 2020
$747kTargeting APOBEC3A-expressing cancer cells with ATR inhibitorsK99CA212154 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI BUISSON, REMI · 2017 to 2018
$285kUnveiling the mechanism for Spartan-mediated DNA lesion bypass and the implications for breast cancer treatmentF32CA192779 · NCI · MASSACHUSETTS GENERAL HOSPITAL · PI MOQUIN, DAVID MARK · 2015 to 2017
$173kThe Role of TFIIB in Transcription ActivationF31GM067388 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ESTRELLA-PEREZ, LUIS A · 2002 to 2004
$71kNCI NIH HHS F32 CA192779NCI NIH HHS K99 CA212154NCI NIH HHS R00 CA212154NCI NIH HHS R01 CA197779NIGMS NIH HHS F31 GM067388NIGMS NIH HHS R01 GM076388NIGMS NIH HHS R01 GM118833
Abstract
Numerous DNA repair and signaling proteins function at DNA damage sites to protect the genome. Here, we show that fusion of the promiscuous biotin ligase BirA
Indexed as
DNA DamageBiotinylationCarbon-Nitrogen LigasesCell LineDNA-Binding ProteinsDNA Breaks, Double-StrandedDNA RepairDNA, Single-StrandedEscherichia coli ProteinsGene Knockdown TechniquesHomologous RecombinationHumansMRE11 Homologue ProteinProtein BindingProtein TransportRepressor ProteinsbirA protein, E coliCarbon-Nitrogen LigasesDNA-Binding ProteinsDNA, Single-StrandedEscherichia coli ProteinsMRE11 Homologue ProteinMRE11 protein, humanRAD18 protein, humanRepressor ProteinsTranscription FactorsUbiquitin-Protein LigasesZNF280C protein, humanDNA damage responseDNA end resectionhomologous recombination
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.