ArticleJournal of virology2019
Endogenous Viral Elements Are Widespread in Arthropod Genomes and Commonly Give Rise to PIWI-Interacting RNAs.
Article in Journal of virology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
71 citing papers in PubMed, 132 citations in OpenAlex.
- Endogenous RNA virus-derived elements exhibit functional divergence in modulating development and virus susceptibility inVirulence · 2026Article
- Identification of Partitivirus-like RdRPs in theViruses · 2026Article
- Transcriptomic and RNAi-mediated antiviral response to Kamiti River virus infection in Aedes albopictus U4.4 cells.Scientific reports · 2026Article
- Evaluating the Effect of Sampling Scale on Mosquito Virome Characterization Using PacBio HiFi Long-Read Metagenomics.Insects · 2026Article
- An endogenous viral element of Aedes albopictus is translated and limits cognate virus.BMC biology · 2026Article
- Article
- New viral sequences and endogenous viral elements (EVE) in world-wide populations of Trioza erytreae, the African citrus psyllid.Virus research · 2026Article
- Tracing ancient viral footprints: a comprehensive study of endogenous viral elements in Bombus species.Mobile DNA · 2026Article
- Monoallelic knockout of r2d2 affects the antiviral RNAi response to Mayaro virus and the reproductive potential in Aedes aegypti.Parasites & vectors · 2026Article
- Comprehensive characterization of non-retroviral endogenous viral elements in the rice pest Chilo suppressalis.BMC genomics · 2025Article
- Analysis of somatic piRNAs in the malaria mosquitoRNA biology · 2025Article
- Diversity and evolutionary history of RNA viruses among different horseshoe crab species.Journal of virology · 2025Article
- Discovery of novel non-retroviral endogenous viral elements reveals their long-term integration history in spiders.Nature communications · 2025Article
- detectEVE: Fast, Sensitive and Precise Detection of Endogenous Viral Elements in Genomic Data.Molecular ecology resources · 2025Article
- Article
- piRNA/PIWI pathways and epigenetic crosstalk in human diseases: Molecular insights into HIV-1 infection and drugs of abuse.Molecular therapy. Nucleic acids · 2025Review
- EEfinder, a general purpose tool for identification of bacterial and viral endogenized elements in eukaryotic genomes.Computational and structural biotechnology journal · 2024Article
- Highly divergent and diverse viral community infecting sylvatic mosquitoes from Northeast Brazil.Journal of virology · 2024Article
- piRNA associates with immune diseases.Cell communication and signaling : CCS · 2024Review
- Metatranscriptomic investigation of singlemSystems · 2024Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arthropod genomes contain sequences derived from integrations of DNA and nonretroviral RNA viruses. These sequences, known as endogenous viral elements (EVEs), have been acquired over the course of evolution and have been proposed to serve as a record of past viral infections. Recent evidence indicates that EVEs can function as templates for the biogenesis of PIWI-interacting RNAs (piRNAs) in some mosquito species and cell lines, raising the possibility that EVEs may serve as a source of immunological memory in these organisms. However, whether piRNAs are derived from EVEs or serve an antiviral function in other arthropod species is unknown. Here, we used publicly available genome assemblies and small RNA sequencing data sets to characterize the repertoire and function of EVEs across 48 arthropod genomes. We found that EVEs are widespread in arthropod genomes and primarily correspond to unclassified single-stranded RNA (ssRNA) viruses and viruses belonging to the
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.