ArticleBMJ open2018
Independent predictors for longer radiographic resolution in patients with refractory
Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.
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Who cites it
33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 40 citations in OpenAlex.
- Prevalence, risk factors, and early prediction of refractory pneumonia caused by Mycoplasma pneumoniae in children: a systematic review and meta-analysis.European journal of pediatrics · 2026Pooled it
- Refractory Mycoplasma Pneumonia in Children: A Systematic Review and Meta-analysis of Laboratory Features and Predictors.Journal of immunology research · 2022Pooled it
- Risk factors for plastic bronchitis complicating severeTranslational pediatrics · 2026Article
- Clinical risk factors and predictive value of thin-section CT for bronchial mucus plugs in pediatric mycoplasma pneumoniae pneumonia.BMC infectious diseases · 2026Article
- Clinical efficacy comparison of Doxycycline versus Azithromycin combined with Methylprednisolone in the treatment of macrolide-unresponsive Mycoplasma pneumoniae pneumonia in children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Efficacy and short-term safety of intravenous omadacycline as second-line therapy for macrolide- unresponsive Mycoplasma pneumoniae pneumonia in children: a retrospective cohort study.Frontiers in cellular and infection microbiology · 2026Article
- The Role of NLR and Ferritin Levels as Biomarkers for Corticosteroid Dosage in Children with RefractoryJournal of inflammation research · 2026Article
- Comparison of Different Corticosteroid Regimens for RefractoryInfection and drug resistance · 2026Article
- [Predictive factors and nomogram model construction for plastic bronchitis in children withZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Factors associated with Mycoplasma pneumoniae-induced Lobar pneumonia with mucus plugging and the optimal timing for bronchoalveolar lavage: a retrospective study.BMC pediatrics · 2025Article
- [Risk factors for hypoxemia in children with severeZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2025Article
- Development of a radiomics-based model using computed tomography imaging to assess the incidence of extrapulmonary organ involvement inFrontiers in medicine · 2025Article
- Advances in adhesion-related pathogenesis inFrontiers in microbiology · 2025Review
- Review
- Clinical profiles of Mycoplasma pneumoniae pneumonia in children with different pleural effusion patterns: a retrospective study.BMC infectious diseases · 2024Article
- Model based on the automated AI-driven CT quantification is effective for the diagnosis of refractory Mycoplasma pneumoniae pneumonia.Scientific reports · 2024Article
- The role of LDH and ferritin levels as biomarkers for corticosteroid dosage in children with refractory Mycoplasma pneumoniae pneumonia.Respiratory research · 2024Article
- Predictive value of bronchoscopy combined with CT score for refractory mycoplasma pneumoniae pneumonia in children.BMC pulmonary medicine · 2024Article
- Early predictors of delayed radiographic resolution of lobar pneumonia caused by Mycoplasma pneumoniae in children: a retrospective study in China.BMC infectious diseases · 2024Article
- Clinical Features and Biomarkers for Early Prediction of Refractory Mycoplasma Pneumoniae Pneumonia in Children.Emergency medicine international · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo examine prospectively the radiographic clearance of refractory
designA prospective cohort study.
settingChildren's Hospital of Soochow University, China.
participantsA total of 187 patients with RMPP treated with bronchoscopy were prospectively enrolled in the study between January 2012 and December 2015.
methodsSerial chest radiographs were obtained after discharge every 4 weeks up to a maximum of 24 weeks after diagnosis or until large infiltration on chest radiographs had resolved. Multivariate logistic regression was performed to identify independent predictors of time to complete radiographic resolution.
resultsOf the 187 patients with RMPP, bronchial mucus plug formation was detected in 73 (39.0%). C reactive protein (CRP) ≥50 mg/L, lactate dehydrogenase (LDH) ≥480 U/L, total fever duration ≥10 days and presence of mucus plugs were associated with longer time to radiographic clearance (all p<0.01). Compared with children without mucus plugs, those with mucus plugs were significantly more likely to have longer time to radiographic clearance (adjusted OR: 11.5; 95% CI 2.5 to 45.7; p<0.01).
conclusionClinicians might use duration of fever, CRP, LDH and presence of mucus plugs as parameters to identify children at a longer time to radiographic clearance in patients with RMPP.
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