Evidence map›Paper›PMID 30567544›Full record

ArticleJournal of neuroinflammation2018

Imaging glial activation in patients with post-treatment Lyme disease symptoms: a pilot study using [

Jennifer M Coughlin, Ting Yang, Alison W Rebman, Kathleen T Bechtold, Yong Du, William B Mathews, Wojciech G Lesniak, Erica A Mihm, Sarah M Frey, Erica S Marshall and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neuroinflammation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 62 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Diagnostics (Basel, Switzerland) · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Neuropsychiatric Lyme Disease and Vagus Nerve Stimulation.Antibiotics (Basel, Switzerland) · 2023
    Review
  13. Review
  14. Language Fluency Deficits in Post-treatment Lyme Disease Syndrome.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2023
    Article
  15. Article
  16. Neuropsychiatric Symptoms and Tick-Borne Diseases.Current topics in behavioral neurosciences · 2023
    Article
  17. Article
  18. Review
  19. Development ofACS chemical neuroscience · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Jennifer M CoughlinDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Ting YangDivision of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Alison W RebmanDivision of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Kathleen T BechtoldDepartment of Physical Medicine and Rehabilitation, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Yong DuRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
William B MathewsRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Wojciech G LesniakRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Erica A MihmDivision of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Sarah M FreyRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Erica S MarshallRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Hailey B RosenthalRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Tristan A ReekieSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Michael KassiouSchool of Chemistry, The University of Sydney, Sydney, NSW, 2006, Australia.
Robert F DannalsRussell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Mark J SoloskiDivision of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
John N AucottDivision of Rheumatology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. jaucott2@jhmi.edu.
Martin G PomperDepartment of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD, USA. mpomper@jhmi.edu.
Johns Hopkins University · USJohns Hopkins Medicine · USUniversity of Sydney · AUUniversity of Baltimore · US

Funding

Training/Dissemination-Resource for Molecular Imaging Agents in Precision MedicineP41EB024495 · NIBIB · UT SOUTHWESTERN MEDICAL CENTER · PI MARTIN G POMPER · 2017 to 2026
$11.8M
Sample Processing and Immunoassay Research CoreP30AR070254 · NIAMS · JOHNS HOPKINS UNIVERSITY · PI CLIFTON O BINGHAM, Antony Rosen · 2016 to 2026
$8.9M
NIAMS NIH HHS P30 AR070254NIBIB NIH HHS P41 EB024495NIH HHS EB024495School of Medicine, Johns Hopkins University none
6 · The paper itself

Abstract

The pathophysiology of post-treatment Lyme disease syndrome (PTLDS) may be linked to overactive immunity including aberrant activity of the brain's resident immune cells, microglia. Here we used [

Indexed as

Positron-Emission TomographyAcetamidesAdolescentAdultAgedApoptosis Regulatory ProteinsBrainCarbon RadioisotopesCognition DisordersFemaleHumansImage Processing, Computer-AssistedLyme NeuroborreliosisMagnetic Resonance ImagingMaleMembrane ProteinsAcetamidesApoptosis Regulatory ProteinsCarbon-11Carbon RadioisotopesFCMR protein, humanMembrane ProteinsN,N-diethyl-2-(2-(4-methoxyphenyl)-5,7-dimethyl-pyrazolo(1,5-a)pyrimidin-3-yl)-acetamidePyrazolesPyrimidines[11C]DPA-713MicrogliaNeuroimagingPost-treatment Lyme disease syndrome

Identifiers

PMID30567544
PMCPMC6299943
OpenAlexW2904775041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.