Evidence map›Paper›PMID 30567381›Full record

ArticleInternational journal of molecular sciences2018

Synthesis and Evaluation of the 4-Substituted 2-Hydroxy-5-Iodochalcones and Their 7-Substituted 6-Iodoflavonol Derivatives for Inhibitory Effect on Cholinesterases and β-Secretase.

Malose J Mphahlele, Emmanuel N Agbo, Samantha Gildenhuys

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. In Vitro Evaluation and Docking Studies of 5-oxo-5International journal of molecular sciences · 2019
    Article
  8. Inhibitory Effects of Novel 7-Substituted 6-iodo-3-Molecules (Basel, Switzerland) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Malose J MphahleleDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa. mphahmj@unisa.ac.za.ORCID 0000-0002-6018-5671
Emmanuel N AgboDepartment of Chemistry, College of Science, Engineering and Technology, University of South Africa, Private Bag X06, Florida 1710, South Africa. Tagboen@unisa.ac.za.
Samantha GildenhuysDepartment of Life & Consumer Sciences, College of Agriculture and Environmental Sciences, University of South Africa, Private Bag X06, Florida 1710, South Africa. gildes@unisa.ac.za.ORCID 0000-0002-9717-8379
University of South Africa · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A series of 2-aryl-3-hydroxy-6-iodo-4

Indexed as

AcetylcholinesteraseAmyloid Precursor Protein SecretasesButyrylcholinesteraseChalconesCholinesterase InhibitorsFlavonoidsHumansKineticsMolecular Docking Simulation3-hydroxyflavoneAcetylcholinesteraseAmyloid Precursor Protein SecretasesButyrylcholinesteraseChalconesCholinesterase InhibitorsFlavonoids4-substituted 2-hydroxy-5-iodochalcones7-substituted 6-iodoflavonolsBACE-1cholinesterasesmolecular dockingX-ray

Identifiers

PMID30567381
PMCPMC6321475
OpenAlexW2904792901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.