Evidence map›Paper›PMID 30567345›Full record

ReviewInternational journal of molecular sciences2018

Pathological Process of Prompt Connection between Host and Donor Tissue Vasculature Causing Rapid Perfusion of the Engineered Donor Tissue after Transplantation.

Sachiko Sekiya, Shunichi Morikawa, Taichi Ezaki, Tatsuya Shimizu

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sachiko SekiyaInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan. sekiya.sachiko@twmu.ac.jp.
Shunichi MorikawaDepartment of Anatomy and Developmental Biology, Tokyo Women's Medical University, Tokyo 162-8666, Japan;ezakit@twmu.ac.jp (T.E.).
Taichi EzakiDepartment of Anatomy and Developmental Biology, Tokyo Women's Medical University, Tokyo 162-8666, Japan;ezakit@twmu.ac.jp (T.E.). ezakit@twmu.ac.jp.
Tatsuya ShimizuInstitute of Advanced Biomedical Engineering and Science, Tokyo Women's Medical University, Tokyo 162-8666, Japan. shimizu.tatsuya@twmu.ac.jp.
Tokyo Women's Medical University · JP

Funding

Japan Society for the Promotion of Science 17H02089Ministry of Education, Culture, Sports, Science and Technology K8
6 · The paper itself

Abstract

The shortage of donors for transplantation therapy is a serious issue worldwide. Tissue engineering is considered a potential solution to this problem. Connection and perfusion in engineered tissues after transplantation is vital for the survival of the transplanted tissue, especially for tissues requiring blood perfusion to receive nutrients, such as the heart. A myocardial cell sheet containing an endothelial cell network structure was fabricated in vitro using cell sheet technology. Transplantation of the three-dimensional (3D) tissue by layering myocardial sheets could ameliorate ischemic heart disease in a rat model. The endothelial cell network in the 3D tissue was able to rapidly connect to host vasculature and begin perfusion within 24 h after transplantation. In this review, we compare and discuss the engineered tissue⁻host vasculature connection process between tissue engineered constructs with hydrogels and cell sheets by histological analysis. This review provides information that may be useful for further improvements of in vivo engineered tissue vascularization techniques.

Indexed as

Neovascularization, PhysiologicTissue EngineeringAnimalsCoronary VesselsDisease Models, AnimalEndothelial CellsHeart TransplantationHumansHydrogelsMyocardial IschemiaMyocytes, CardiacRatsHydrogelshost–donortissue engineeringtransplantationvasculature connection

Identifiers

PMID30567345
PMCPMC6321572
OpenAlexW2905011158

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.