Evidence map›Paper›PMID 30567230›Full record

ArticleBMJ case reports2018

Case of olmesartan-associated enteropathy and transient positive antitissue transglutaminase serology.

Jenan Ghaith, Ismail A Raslan, Andrew Szilagyi, Mona Alameldin

Open access · hybridAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Jenan GhaithInternal Medicine Residency Program, University of McGill, Montreal, Quebec, Canada.ORCID http://orcid.org/0000-0002-7003-1131
Ismail A RaslanInternal Medicine Residency Program, University of McGill, Montreal, Quebec, Canada.
Andrew SzilagyiMedicine Division of Gastroenterology, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada.
Mona AlameldinDepartment of Pathology, Sir Mortimer B Davis Jewish General Hospital, Montreal, Quebec, Canada.
Jewish General Hospital · CAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Olmesartan-associated enteropathy (OAE) is increasingly being recognised as a major differential diagnosis in patients with villous atrophy and negative coeliac disease (CD) serology. OAE and positive coeliac markers have rarely been reported. We report a case of diarrhoea and small bowel villous blunting associated with a transient elevation of antitissue transglutaminase antibody (ATTG). On discontinuation of olmesartan, symptoms improved, repeat biopsies were normal and levels of ATTG also returned normal. We discuss a possible explanation for the transient elevation in ATTG and the significance of considering OAE/CD overlap.

Indexed as

AntibodiesAntihypertensive AgentsAtrophyCeliac DiseaseDiagnosis, DifferentialFemaleHumansImidazolesIntestine, SmallMiddle AgedTetrazolesTransglutaminasesAntibodiesAntihypertensive AgentsImidazolesolmesartanTetrazolesTransglutaminasescoeliac diseasedrug interactionsdrugs: gastrointestinal systemgastrointestinal systemmalabsorption

Identifiers

PMID30567230
PMCPMC6301511
OpenAlexW2904506320

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.