Evidence map›Paper›PMID 30566934›Full record

ArticleHormone research in paediatrics2018

Parent-Rated Severity of Illness and Anxiety among Caregivers of Children Born with a Disorder of Sex Development Including Ambiguous Genitalia.

Christina M Sharkey, Dana M Bakula, Cortney Wolfe-Christensen, Paul Austin, Laurence Baskin, Kerlly J Bernabé, Yee-Ming Chan, Earl Y Cheng, Alexandria M Delozier, David A Diamond and 19 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Hormone research in paediatrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors.

Christina M SharkeyDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA, christina.sharkey@okstate.edu.
Dana M BakulaDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
Cortney Wolfe-ChristensenCook Children's Medical Center, Fort Worth, Texas, USA.
Paul AustinTexas Children's Hospital, Houston, Texas, USA.
Laurence BaskinUniversity of California San Francisco Medical Center, San Francisco, California, USA.
Kerlly J BernabéKomansky Children's Hospital, New York Presbyterian Weill Cornell Medicine, New York, New York, USA.
Yee-Ming ChanChildren's Hospital Boston, Boston, Massachusetts, USA.
Earl Y ChengAnn and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Alexandria M DelozierDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
David A DiamondChildren's Hospital Boston, Boston, Massachusetts, USA.
Rebecca E H EllensChildren's Hospital of Michigan, Detroit, Michigan, USA.
Allyson FriedOishei Children's Hospital, Buffalo, New York, USA.
Denise GalanKomansky Children's Hospital, New York Presbyterian Weill Cornell Medicine, New York, New York, USA.
Saul GreenfieldOishei Children's Hospital, Buffalo, New York, USA.
Thomas KolonChildren's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Bradley KroppCook Children's Medical Center, Fort Worth, Texas, USA.
Yegappan LakshmananChildren's Hospital of Michigan, Detroit, Michigan, USA.
Sabrina MeyerOishei Children's Hospital, Buffalo, New York, USA.
Theresa MeyerAnn and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
Natalie J NokoffUniversity of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Kristy J Scott ReyesCook Children's Medical Center, Fort Worth, Texas, USA.
Blake PalmerCook Children's Medical Center, Fort Worth, Texas, USA.
Dix P PoppasKomansky Children's Hospital, New York Presbyterian Weill Cornell Medicine, New York, New York, USA.
Alethea ParadisSt. Louis Children's Hospital, St. Louis, Missouri, USA.
Amy TishelmanChildren's Hospital Boston, Boston, Massachusetts, USA.
Elizabeth B YerkesAnn and Robert H. Lurie Children's Hospital of Chicago, Chicago, Illinois, USA.
John M ChaneyDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.
Amy B WisniewskiCook Children's Medical Center, Fort Worth, Texas, USA.
Larry L MullinsDepartment of Psychology, Oklahoma State University, Stillwater, Oklahoma, USA.

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Short-term outcomes of interventions for reproductive dysfunctionR01HD074579 · NICHD · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI MULLINS, LARRY L., WISNIEWSKI, AMY B · 2013 to 2022
$4.3M
NCATS NIH HHS UL1 TR002384NICHD NIH HHS R01 HD074579
6 · The paper itself

Abstract

BACKGROUND/

aimsParents of children born with disorders of sex development (DSD) often experience anxiety, but risk factors, including parental perception of the severity of their child's DSD, have not been examined. We hypothesized that severity of illness (SOI) ratings would relate to parental anxiety, and would be higher for parents of children with a potentially life-threatening DSD (e.g., 21-hydroxylase deficiency).

methodsEighty-nine parents (Mage = 33.0, 56.2% mothers) of 51 children (Mage in months = 8.7) with a DSD including ambiguous genitalia were recruited from 12 specialized DSD clinics. Parents completed questionnaires prior to genitoplasty, 6 months post-genitoplasty, and 12 months post-genitoplasty (if completed). Data were analyzed with linear mixed modeling.

resultsParental anxiety decreased over time, χ2(1) = 10.14, p < 0.01. A positive relationship between SOI and anxiety was found, with SOI being a strong predictor of anxiety (b = 0.53, p < 0.01; χ2[1] = 5.33, p < 0.05). An SOI by time interaction indicated SOI had an increasing effect on anxiety over time, b = 0.06, p < 0.05; χ2(1) = 6.30, p < 0.05. There was no diagnosis by SOI interaction.

conclusionParental anxiety decreased over time, but those with higher SOI ratings reported greater initial anxiety followed by slower resolution over time. Underlying etiology of DSD had no effect on the relationship between SOI and anxiety.

Indexed as

PerceptionAdultAnxietyCaregiversDisorders of Sex DevelopmentFemaleHumansMaleParentsQuality of LifeRisk FactorsSeverity of Illness IndexSurveys and QuestionnairesAnxietyDisorders of sex developmentPsychological aspects of disordersSeverity of illness

Identifiers

PMID30566934
PMCPMC6421083

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.