Evidence map›Paper›PMID 30566877›Full record

ArticleCell reports2018

De Novo Sequence and Copy Number Variants Are Strongly Associated with Tourette Disorder and Implicate Cell Polarity in Pathogenesis.

Sheng Wang, Jeffrey D Mandell, Yogesh Kumar, Nawei Sun, Montana T Morris, Juan Arbelaez, Cara Nasello, Shan Dong, Clif Duhn, Xin Zhao and 25 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. New insights from the last decade of research in psychiatric genetics: discoveries, challenges and clinical implications.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2023
    Article
  11. Review
  12. Article
  13. Review
  14. Networks in the Field of Tourette Syndrome.Frontiers in neurology · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors.

Sheng Wang
Jeffrey D Mandell
Yogesh Kumar
Nawei Sun
Montana T Morris
Juan Arbelaez
Cara Nasello
Shan Dong
Clif Duhn
Xin Zhao
Zhiyu Yang
Shanmukha S Padmanabhuni
Dongmei Yu
Robert A King
Andrea Dietrich
Najah Khalifa
Niklas Dahl
Alden Y Huang
Benjamin M Neale
Giovanni Coppola
Carol A Mathews
Jeremiah M Scharf
Tourette International Collaborative Genetics Study (TIC Genetics)
Tourette Syndrome Genetics Southern and Eastern Europe Initiative (TSGENESEE)
Tourette Association of America International Consortium for Genetics (TAAICG)
Thomas V Fernandez
Joseph D Buxbaum
Silvia De Rubeis
Dorothy E Grice
Jinchuan Xing
Gary A Heiman
Jay A Tischfield
Peristera Paschou
A Jeremy Willsey
Matthew W State

Funding

Neurogenetic Investigations of Obsessive-Compulsive DisorderR01MH114927 · NIMH · YALE UNIVERSITY · PI FERNANDEZ, THOMAS V · 2018 to 2022
$2.8M
Refining the Tourette Syndrome phenotype across diagnoses to aid gene discoveryR01MH096767 · NIMH · UNIVERSITY OF FLORIDA · PI MATHEWS, CAROL A · 2013 to 2015
$1.2M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysisS10OD030363 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2022 to 2022
$1.2M
High Performance Computing Instrumentation for the Yale Center for Genome AnalysiS10OD018521 · OD · YALE UNIVERSITY · PI MANE, SHRIKANT M · 2015 to 2015
$890k
Genomic Investigations of Tourette's DisorderK08MH099424 · NIMH · YALE UNIVERSITY · PI FERNANDEZ, THOMAS V · 2012 to 2015
$718k
NIH HHS S10 OD018521NIH HHS S10 OD030363NIMH NIH HHS K08 MH099424NIMH NIH HHS L40 MH081784NIMH NIH HHS R01 MH096767NIMH NIH HHS R01 MH114927
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.