ArticleCell reports2018
Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity.
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Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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27citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
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Who cites it
27 citing papers in PubMed, 43 citations in OpenAlex.
- BCL6 regulates skeletal muscle mass and mitochondrial bioenergetics.Molecular metabolism · 2026Article
- Hypothalamic BCL6 signaling modulates energy homeostasis and metabolism by inhibiting STAT3 transcription.Journal of advanced research · 2026Article
- Blood biomarkers and breed genetics of aging in pet dogs.bioRxiv : the preprint server for biology · 2026Article
- Article
- The potential role of serum miR-182-5p and miR-127-5p in diagnosis of metabolic dysfunction-associated steatotic liver disease and its relationship with insulin resistance.Przeglad gastroenterologiczny · 2026Article
- Curcumin ameliorates hepatic steatosis and insulin resistance through the JNK2/FOXO1/Bcl6 axis and regulate the intestinal flora structure.Journal of physiology and biochemistry · 2025Article
- The effect of aldafermin expressing-Escherichia coli Nissle 1917 along with dietary change on visceral adipose tissue in MASLD mouse model.International journal of obesity (2005) · 2025Article
- The measurement, regulation and biological activity of FAHFAs.Nature chemical biology · 2025Review
- Adipose tissue-derived microRNA-450a-5p induces type 2 diabetes mellitus by downregulating DUSP10.Molecular biomedicine · 2025Article
- BCL6 coordinates muscle mass homeostasis with nutritional states.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- B Cell Lymphoma 6 (BCL6): A Conserved Regulator of Immunity and Beyond.International journal of molecular sciences · 2024Review
- Transcription factor PATZ1 promotes adipogenesis by controlling promoter regulatory loci of adipogenic factors.Nature communications · 2024Article
- Article
- Transcriptional programming of translation by BCL6 controls skeletal muscle proteostasis.Nature metabolism · 2024Article
- Pannexin-3 stabilizes the transcription factor Bcl6 in a channel-independent manner to protect against vascular oxidative stress.Science signaling · 2024Article
- DIDO is necessary for the adipogenesis that promotes diet-induced obesity.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Article
- Bioinformatics Analysis of Next Generation Sequencing Data Identifies Molecular Biomarkers Associated With Type 2 Diabetes Mellitus.Clinical medicine insights. Endocrinology and diabetes · 2023Article
- B-cell lymphoma 6 alleviates nonalcoholic fatty liver disease in mice through suppression of fatty acid transporter CD36.Cell death & disease · 2022Article
- Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
13 authors at 4 institutions in 1 country.
Madhavi D SenagolageDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Meredith A SommarsDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Krithika RamachandranDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Christopher R FuttnerDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Yasuhiro OmuraDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Amanda L AllredDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.
Jianing WangBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA.
Cynthia YangCenter for Translational Imaging, Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA.
Daniele ProcissiCenter for Translational Imaging, Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL 60611, USA.
Ronald M EvansHoward Hughes Medical Institute, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Xianlin HanBarshop Institute for Longevity and Aging Studies, University of Texas Health Science Center at San Antonio, San Antonio, TX 78245, USA.
Ilya R BedermanDepartment of Pediatrics, Case Western Reserve University, Cleveland, OH 44106, USA.
Grant D BarishDivision of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA. Electronic address: grant.barish@northwestern.edu.
Northwestern University · USThe University of Texas Health Science Center at San Antonio · USCase Western Reserve University · USSalk Institute for Biological Studies · US
Funding
Tumor Environment and Metastasis (TEAM) Research ProgramP30CA060553 · NCI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LEONIDAS C. PLATANIAS · 1993 to 2026
$153.9MViral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Alan Saghatelian · 1985 to 2026
$82.8MPilot and Feasibility ProgramP30DK020595 · NIDDK · UNIVERSITY OF CHICAGO · PI Raghavendra G Mirmira · 2013 to 2026
$20.9MHORMONAL REGULATION OF MAMMALIAN GENE EXPRESSIONR37DK057978 · NIDDK · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI EVANS, RONALD M · 2000 to 2019
$16.0MSpatial Regulation of Developmental Gene ExpressionR01HL105278 · NHLBI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI EVANS, RONALD M · 2011 to 2019
$4.0MNuclear Repressors in Genomic Control of Healthful ObesityR01DK108987 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI BARISH, GRANT D · 2016 to 2024
$3.4MHormonal Regulation of Mammalian Gene ExpressionR01DK057978 · NIDDK · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI EVANS, RONALD M · 2021 to 2024
$2.6MRepressor-PPAR Interactions in Inflammation and AtherosclerosisK08HL092298 · NHLBI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI BARISH, GRANT D · 2009 to 2013
$609kNCI NIH HHS P30 CA014195NCI NIH HHS P30 CA060553NHLBI NIH HHS K08 HL092298NHLBI NIH HHS R01 HL105278NIDDK NIH HHS P30 DK020595NIDDK NIH HHS R01 DK057978NIDDK NIH HHS R01 DK108987NIDDK NIH HHS R37 DK057978
Abstract
Accumulation of visceral adiposity is directly linked to the morbidity of obesity, while subcutaneous body fat is considered more benign. We have identified an unexpected role for B cell lymphoma 6 (BCL6), a critical regulator of immunity, in the developmental expansion of subcutaneous adipose tissue. In adipocyte-specific knockout mice (Bcl6
Indexed as
Insulin ResistanceTranscription, Genetic3T3-L1 CellsAdipocytesAdiponectinAdipose Tissue, BrownAdiposityAnimalsCell DifferentiationDiet, High-FatDNAFatty LiverFetusGene Expression RegulationHumansInflammationAdiponectinBcl6 protein, mouseDNAInsulinLipidsProto-Oncogene Proteins c-bcl-6adipocyteadiponectinadipose tissueBCL-6BCL6ceramideFAHFAfatty acid esters of hydroxy fatty acidshypertrophyinsulin sensitivitylipogenesisobesityPAHSArepressorsubcutaneous fat
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Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.