ArticlePloS one2018
Thalamic shape and volume abnormalities in female patients with panic disorder.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Grey matter structural alterations in anxiety disorders: a voxel-based meta-analysis.Brain imaging and behavior · 2024Pooled it
- Chemokine-complement cascade in glial-vascular units protects neurons from non-biogenic nanoparticles.Journal of neuroinflammation · 2025Article
- Brain volumes, behavioral inhibition, and anxiety disorders in children: results from the adolescent brain cognitive development study.BMC psychiatry · 2024Article
- Exploring Brainstem Structural Abnormalities: Potential Biomarkers for Panic Disorder.Experimental neurobiology · 2024Article
- Impact of Stress on Brain Morphology: Insights into Structural Biomarkers of Stress-related Disorders.Current neuropharmacology · 2024Review
- Anxiety in children and youth with autism spectrum disorder and the association with amygdala subnuclei structure.Autism : the international journal of research and practice · 2023Article
- Differences in resting-state brain networks and gray matter between APOE ε2 and APOE ε4 carriers in non-dementia elderly.Frontiers in psychiatry · 2023Article
- Association between startle reactivity to uncertain threats and structural brain volume.Psychophysiology · 2022Article
- Effects of Acupuncture at Neiguan in Neural Activity of Related Brain Regions: A Resting-State fMRI Study in Anxiety.Neuropsychiatric disease and treatment · 2022Article
- Glutamic Acid Decarboxylase 1 Gene Methylation and Panic Disorder Severity: Making the Connection by Brain Gray Matter Volume.Frontiers in psychiatry · 2022Article
- Volume reduction without neuronal loss in the primate pulvinar complex following striate cortex lesions.Brain structure & function · 2021Article
- Oxytocin Signaling Acts as a Marker for Environmental Stressors in Zebrafish.International journal of molecular sciences · 2021Article
- Shared and unique neural circuitry underlying temporally unpredictable threat and reward processing.Social cognitive and affective neuroscience · 2021Article
- Smaller volume of right hippocampal CA2/3 in patients with panic disorder.Brain imaging and behavior · 2021Article
- Multimodal MRI Assessment of Thalamic Structural Changes in Earthquake Survivors.Diagnostics (Basel, Switzerland) · 2021Article
- The modulating impact of cigarette smoking on brain structure in panic disorder: a voxel-based morphometry study.Social cognitive and affective neuroscience · 2020Article
- Asymmetrical atrophy of thalamic subnuclei in Alzheimer's disease and amyloid-positive mild cognitive impairment is associated with key clinical features.Alzheimer's & dementia (Amsterdam, Netherlands) · 2019Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The thalamus is believed to play crucial role in processing viscero-sensory information, and regulating the activity of amygdala in patients with panic disorder (PD). Previous functional neuroimaging studies have detected abnormal activation in the thalamus in patients with PD compared with healthy control subjects (HC). Very few studies, however, have investigated for volumetric abnormalities in the thalamus in patients with PD. Furthermore, to the best of our knowledge, no previous study has investigated for shape abnormalities in the thalamus in patients with PD. Twenty-five patients with PD and 25 HC participants (all female) were recruited for the study. A voxel-wise volume comparison analysis and a vertex-wise shape analysis were conducted to evaluate structural abnormalities in the PD patients compared to HC. The patients with PD demonstrated significant gray matter volume reductions in the thalamus bilaterally, relative to the HC. The shape analysis detected significant inward deformation in some thalamic regions in the PD patients, including the anterior nucleus, mediodorsal nucleus, and pulvinar nucleus. PD patients showed shape deformations in key thalamic regions that are believed to play a role in regulating emotional and cognitive functions.
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