Evidence map›Paper›PMID 30566466›Full record

Trial reportPloS one2018

Molecular detection of dengue virus in patients suspected of Ebola virus disease in Ghana.

Joseph Humphrey Kofi Bonney, Takaya Hayashi, Samuel Dadzie, Esinam Agbosu, Deborah Pratt, Stephen Nyarko, Franklin Asiedu-Bekoe, Eiji Ido, Badu Sarkodie, Nobuo Ohta and 1 more

Open access · goldAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.

  1. Analysis of dengue fever disease in West Africa.Experimental biology and medicine (Maywood, N.J.) · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Joseph Humphrey Kofi BonneyVirology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.ORCID 0000-0003-0301-8145
Takaya HayashiVirology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.
Samuel DadzieVirology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.
Esinam AgbosuVirology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.
Deborah PrattVirology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.
Stephen NyarkoVirology Department, Noguchi Memorial Institute of Medical Research, University of Ghana, Legon, Ghana.
Franklin Asiedu-BekoeDisease Surveillance Department, Ghana Health Service, Accra, Ghana.ORCID 0000-0002-0691-5020
Eiji IdoTokyo Medical and Dental University, Tokyo, Japan.
Badu SarkodiePublic Health Division, Ghana Health Service, Accra, Ghana.
Nobuo OhtaTokyo Medical and Dental University, Tokyo, Japan.
Shoji YamaokaTokyo Medical and Dental University, Tokyo, Japan.
University of Ghana · GHTokyo Medical and Dental University · JPGhana Health Service · GH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dengue fever is known to be one of the most common arthropod-borne viral infectious diseases of public health importance. The disease is now endemic in more than 100 countries in Africa, the Americas, the Eastern Mediterranean, Southeast Asia and the Western Pacific with an estimated two fifths of the world's population being at risk. The notable endemic viral hemorrhagic fevers (VHFs) found in West Africa, including yellow fever, Lassa fever, Rift Valley fever, dengue fever and until recently Ebola have been responsible for most outbreaks with fatal consequences. These VHFs usually produce unclear acute febrile illness, especially in the acute phase of infection. In this study we detected the presence of 2 different serotypes (DENV-2 and DENV-3) of Dengue virus in 4 sera of 150 patients clinically suspected of Ebola virus disease during the Ebola Virus Disease (EVD) outbreak in West Africa with the use of serological and molecular test assays. Sequence data was successfully generated for DENV-3 and phylogenetic analysis of the envelope gene showed that the DENV-3 sequences had close homology with DENV-3 sequences from Senegal and India. This study documents molecular evidence of an indigenous Dengue fever viral infection in Ghana and therefore necessitates the need to have an efficient surveillance system to rapidly detect and control the dissemination of the different serotypes in the population which has the potential to cause outbreaks of dengue hemorrhagic fevers.

Indexed as

DengueHemorrhagic Fever, EbolaDengue VirusDisease OutbreaksEbolavirusFemaleGhanaHumansMale

Identifiers

PMID30566466
PMCPMC6300295
OpenAlexW2905012492

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.