Evidence map›Paper›PMID 30566451›Full record

ArticlePloS one2018

Epidemiology and treatment patterns of rheumatoid arthritis in a large cohort of Arab patients.

Soha R Dargham, Sumeja Zahirovic, Mohammed Hammoudeh, Samar Al Emadi, Basel K Masri, Hussein Halabi, Humeira Badsha, Imad Uthman, Ziyad R Mahfoud, Hadil Ashour and 7 more

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  4. Association ofPharmaceuticals (Basel, Switzerland) · 2025
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Soha R DarghamWeill Cornell Medicine-Qatar, Education City, Doha, Qatar.ORCID 0000-0003-2695-6564
Sumeja ZahirovicWeill Cornell Medicine-Qatar, Education City, Doha, Qatar.ORCID 0000-0002-0221-1800
Mohammed HammoudehHamad Medical Corporation, Doha, Qatar.
Samar Al EmadiHamad Medical Corporation, Doha, Qatar.
Basel K MasriJordan Hospital, Amman, Jordan.
Hussein HalabiKing Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Humeira BadshaDr. Humeira Badsha Medical Center, Dubai, United Arab Emirates.
Imad UthmanAmerican University of Beirut, Beirut, Lebanon.
Ziyad R MahfoudWeill Cornell Medicine-Qatar, Education City, Doha, Qatar.
Hadil AshourHamad Medical Corporation, Doha, Qatar.
Wissam Gad El HaqHamad Medical Corporation, Doha, Qatar.
Karim BayoumyHamad Medical Corporation, Doha, Qatar.
Marianthi KapiriWeill Cornell Medicine-Qatar, Education City, Doha, Qatar.
Richa SaxenaMassachusetts General Hospital, Boston, Massachusetts, United States of America.
Robert M PlengeBroad Institute, Cambridge, Massachusetts, United States of America.
Layla KazkazTishreen University, Latakia, Syria.
Thurayya ArayssiWeill Cornell Medicine-Qatar, Education City, Doha, Qatar.ORCID 0000-0003-2469-0272

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThere is limited information on the epidemiology and treatment patterns of rheumatoid arthritis (RA) across the Arab region. We aim in this study to describe the demographic characteristics, clinical profile, and treatment patterns of patients of Arab ancestry with RA.

methodsThis is a cross sectional study of 895 patients with established rheumatoid arthritis enrolled from five sites (Jordan, Lebanon, Qatar, Kingdom of Saudi Arabia (KSA), and United Arab Emirates). Demographic characteristics, clinical profile, and treatment patterns are compared between the five countries.

resultsThe majority of our patients are women, have an average disease duration of 10 years, are married and non-smokers, with completed secondary education. We report a high (>80%) ever-use of methotrexate (MTX) and steroids among our RA population, while the ever-use of disease modifying anti-rheumatic drugs (DMARDs) and TNF-inhibitors average around 67% and 33%, respectively. There are variations in RA treatment use between the five country sites. Highest utilization of steroids is identified in Jordan and KSA (p-value < 0.001), while the highest ever-use of TNF-inhibitors is reported in KSA (p-value < 0.001).

conclusionDisparities in usage of RA treatments among Arab patients are noted across the five countries. National gross domestic product (GDP), as well as some other unique features in each country likely affect these. Developing treatment guidelines specific to this region could contribute in delivering standardized therapies to RA patients.

Indexed as

AdultAntirheumatic AgentsArthritis, RheumatoidCross-Sectional StudiesEtanerceptFemaleHumansJordanLebanonMaleMethotrexateMiddle AgedOdds RatioQatarSaudi ArabiaUnited Arab EmiratesAntirheumatic AgentsEtanerceptMethotrexate

Identifiers

PMID30566451
PMCPMC6300286

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.