ArticlePLoS genetics2018
RSM1, an Arabidopsis MYB protein, interacts with HY5/HYH to modulate seed germination and seedling development in response to abscisic acid and salinity.
Article in PLoS genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
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Who cites it
40 citing papers in PubMed, 92 citations in OpenAlex.
- Larix gmelinii UGPase enhances vegetative growth in transgenic poplar through an HYH-mediated positive feedback loop.Plant cell reports · 2026Article
- Holistic overview of regulatory networks governing seed dormancy and germination in plants.Science China. Life sciences · 2026Review
- Early transcriptomic changes in cucumber and maize roots in response to FePOScientific reports · 2025Article
- CmBr confers fruit bitterness under CPPU treatment in melon.Plant biotechnology journal · 2024Article
- Far-red light modulates grapevine growth by increasing leaf photosynthesis efficiency and triggering organ-specific transcriptome remodelling : Author.BMC plant biology · 2024Article
- Article
- Characteristics and Functions of MYB (v-Myb avivan myoblastsis virus oncogene homolog)-Related Genes inGenes · 2023Review
- Function of Transcription FactorsInternational journal of molecular sciences · 2023Article
- Genome-Wide Identification and Expression Analysis of the RADIALIS-like Gene Family inPlants (Basel, Switzerland) · 2023Article
- CRISPR/Cas9-MediatedInternational journal of molecular sciences · 2023Article
- Genomic survey of MYB gene family in six pearl millet (Pennisetum glaucum) varieties and their response to abiotic stresses.Genetica · 2023Article
- Triphosphate Tunnel Metalloenzyme 2 Acts as a Downstream Factor of ABI4 in ABA-Mediated Seed Germination.International journal of molecular sciences · 2023Article
- Jasmonic acid regulates the biosynthesis of medicinal metabolites via the JAZ9-MYB76 complex inHorticulture research · 2023Article
- A MYB-related transcription factor from peanut, AhMYB30, improves freezing and salt stress tolerance in transgenicFrontiers in plant science · 2023Article
- Network of the transcriptome and metabolomics reveals a novel regulation of drought resistance during germination in wheat.Annals of botany · 2022Article
- Salt Stress Tolerance inPlants (Basel, Switzerland) · 2022Article
- Plant hormone regulation of abiotic stress responses.Nature reviews. Molecular cell biology · 2022Review
- TDTHub, a web server tool for the analysis of transcription factor binding sites in plants.The Plant journal : for cell and molecular biology · 2022Article
- Genome-Wide Identification of R2R3-MYB Transcription Factor and Expression Analysis under Abiotic Stress in Rice.Plants (Basel, Switzerland) · 2022Article
- CONSTITUTIVE PHOTOMORPHOGENIC 1 promotes seed germination by destabilizing RGA-LIKE 2 in Arabidopsis.Plant physiology · 2022Article
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
MYB transcription factors are involved in many biological processes, including metabolism, development and responses to biotic and abiotic stresses. RADIALIS-LIKE SANT/MYB 1 (RSM1) belongs to a MYB-related subfamily, and previous transcriptome analysis suggests that RSM1 may play roles in plant development, stress responses and plant hormone signaling. However, the molecular mechanisms of RSM1 action in response to abiotic stresses remain obscure. We show that down-regulation or up-regulation of RSM1 expression alters the sensitivity of seed germination and cotyledon greening to abscisic acid (ABA), NaCl and mannitol in Arabidopsis. The expression of RSM1 is dynamically regulated by ABA and NaCl. Transcription factors ELONGATED HYPOCOTYL 5 (HY5) and HY5 HOMOLOG (HYH) regulate RSM1 expression via binding to the RSM1 promoter. Genetic analyses reveal that RSM1 mediates multiple functions of HY5 in responses of seed germination, post-germination development to ABA and abiotic stresses, and seedling tolerance to salinity. Pull-down and BiFC assays show that RSM1 interacts with HY5/HYH in vitro and in vivo. RSM1 and HY5/HYH may function as a regulatory module in responses to ABA and abiotic stresses. RSM1 binds to the promoter of ABA INSENSITIVE 5 (ABI5), thereby regulating its expression, while RSM1 interaction also stimulates HY5 binding to the ABI5 promoter. However, no evidence was found in the dual-luciferase transient expression assay to support that RSM enhances the activation of ABI5 expression by HY. In summary, HY5/HYH and RSM1 may converge on the ABI5 promoter and independently or somehow dependently regulate ABI5 expression and ABI5-downstream ABA and abiotic stress-responsive genes, thereby improving the adaption of plants to the environment.
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